期刊
MOLECULES
卷 20, 期 8, 页码 14155-14190出版社
MDPI
DOI: 10.3390/molecules200814155
关键词
graphene; graphene oxide; graphene-based nanomaterials; peroxidases; enzyme mimetics; heterogeneous catalysts; biosensing and diagnostics; tetramethylbenzidine; hydrogen peroxide
资金
- Ministry of Science and Technology [NSC101-2113-M-007-006-MY3, MOST104-2881-M-007-039, MOST104-2113-M-007-008-MY3]
- National Tsing Hua University (NTHU) of Taiwan [104N1807E1]
Artificial enzymes, a term coined by Breslow for enzyme mimics is an exciting and promising branch of biomimetic chemistry aiming to imitate the general and essential principles of natural enzymes using a variety of alternative materials including heterogeneous catalysts. Peroxidase enzymes represent a large family of oxidoreductases that typically catalyze biological reactions with high substrate affinity and specificity under relatively mild conditions and thus offer a wide range of practical applications in many areas of science. The increasing understanding of general principles as well as intrinsic drawbacks such as low operational stability, high cost, difficulty in purification and storage, and sensitivity of catalytic activity towards atmospheric conditions of peroxidases has triggered a dynamic field in nanotechnology, biochemical, and material science that aims at joining the better of three worlds by combining the concept adapted from nature with the processability of catalytically active graphene-based nanomaterials (G-NMs) as excellent peroxidase mimetic catalysts. This comprehensive review discusses an up-to-date synthesis, kinetics, mechanisms, and biosensing applications of a variety of G-NMs that have been explored as promising catalysts to mimic natural peroxidases.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据