期刊
MOLECULES
卷 20, 期 4, 页码 7245-7262出版社
MDPI
DOI: 10.3390/molecules20047245
关键词
serrulatane derivatives; leubethanol; semi-synthesis; in vitro antimycobacterial activity; cytotoxicity assay
资金
- Mexican Network (PROMEP)
- ISCIII-RICET
- CONACYT, Mexico
Seventeen new derivatives of the natural diterpene leubethanol, including some potential pro-drugs, with changes in the functionality of the aliphatic chain or modifications of aromatic ring and the phenolic group, were synthesized and tested in vitro by the MABA technique for their activity against the H37Rv strain of Mycobacterium tuberculosis. Some compounds showed antimycobacterial selectivity indices higher than leubethanol.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据