相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Homology and Molecular Dynamics Models of Toll-Like Receptor 7 Protein and Its Dimerization
Chih-Yuan Tseng et al.
CHEMICAL BIOLOGY & DRUG DESIGN (2014)
Imiquimod in the Treatment of Breast Cancer Skin Metastasis
Lisa Henriques et al.
JOURNAL OF CLINICAL ONCOLOGY (2014)
TLR7/8 agonists trigger immunostimulatory properties of human 6-sulfo LacNAc dendritic cells
Hanka Jaehnisch et al.
CANCER LETTERS (2013)
Resiquimod, a topical drug for viral skin lesions and skin cancer
Thomas Meyer et al.
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2013)
Processing of Human Toll-like Receptor 7 by Furin-like Proprotein Convertases Is Required for Its Accumulation and Activity in Endosomes
Madeleine M. Hipp et al.
IMMUNITY (2013)
Routine Microsecond Molecular Dynamics Simulations with AMBER on GPUs. 2. Explicit Solvent Particle Mesh Ewald
Romelia Salomon-Ferrer et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2013)
Toll-Like Receptor 7 Agonists: Chemical Feature Based Pharmacophore Identification and Molecular Docking Studies
Hui Yu et al.
PLOS ONE (2013)
Structural Reorganization of the Toll-Like Receptor 8 Dimer Induced by Agonistic Ligands
Hiromi Tanji et al.
SCIENCE (2013)
New developments in Toll-like receptor targeted therapeutics
Dympna J. Connolly et al.
CURRENT OPINION IN PHARMACOLOGY (2012)
Homology Modeling a Fast Tool for Drug Discovery: Current Perspectives
V. K. Vyas et al.
INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES (2012)
The application of Toll like receptors for cancer therapy
Eui Young So et al.
International Journal of Biological Sciences (2012)
The Normal-Mode Entropy in the MM/GBSA Method: Effect of System Truncation, Buffer Region, and Dielectric Constant
Samuel Genheden et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2012)
MMPBSA.py: An Efficient Program for End-State Free Energy Calculations
Bill R. Miller et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2012)
Routine Microsecond Molecular Dynamics Simulations with AMBER on GPUs. 1. Generalized Born
Andreas W. Goetz et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2012)
Toll-like receptor 7 regulates pancreatic carcinogenesis in mice and humans
Atsuo Ochi et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
Variability in docking success rates due to dataset preparation
Christopher R. Corbeil et al.
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN (2012)
Negative Regulation of the Type I Interferon Signaling Pathway by Synthetic Toll-Like Receptor 7 Ligands
Alexandra Forsbach et al.
JOURNAL OF INTERFERON AND CYTOKINE RESEARCH (2012)
Asparagine Endopeptidase Controls Anti-Influenza Virus Immune Responses through TLR7 Activation
Sophia Maschalidi et al.
PLOS PATHOGENS (2012)
Toll-Like Receptor 7 Agonist Therapy with Imidazoquinoline Enhances Cancer Cell Death and Increases Lymphocytic Infiltration and Proinflammatory Cytokine Production in Established Tumors of a Renal Cell Carcinoma Mouse Model
Eric C. Kauffman et al.
JOURNAL OF ONCOLOGY (2012)
Assessing the Performance of the MM/PBSA and MM/GBSA Methods. 1. The Accuracy of Binding Free Energy Calculations Based on Molecular Dynamics Simulations
Tingjun Hou et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2011)
A Point Mutation in the Amino Terminus of TLR7 Abolishes Signaling without Affecting Ligand Binding
Carlo Iavarone et al.
JOURNAL OF IMMUNOLOGY (2011)
The TLR7 Ligand 9-Benzyl-2-Butoxy-8-Hydroxy Adenine Inhibits IL-17 Response by Eliciting IL-10 and IL-10-Inducing Cytokines
Alessandra Vultaggio et al.
JOURNAL OF IMMUNOLOGY (2011)
A leucine-rich repeat assembly approach for homology modeling of the human TLR5-10 and mouse TLR11-13 ectodomains
Tiandi Wei et al.
JOURNAL OF MOLECULAR MODELING (2011)
Additive melanoma suppression with intralesional phospholipid-conjugated TLR7 agonists and systemic IL-2
Tomoko Hayashi et al.
MELANOMA RESEARCH (2011)
UniProt Knowledgebase: a hub of integrated protein data
Michele Magrane
DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION (2011)
Dual or Triple Activation of TLR7, TLR8, and/or TLR9 by Single-Stranded Oligoribonucleotides
Alexandra Forsbach et al.
NUCLEIC ACID THERAPEUTICS (2011)
Impaired Expression and Function of Toll-like Receptor 7 in Hepatitis C Virus Infection in Human Hepatoma Cells
Serena Chang et al.
HEPATOLOGY (2010)
AutoDock4 and AutoDockTools4: Automated Docking with Selective Receptor Flexibility
Garrett M. Morris et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2009)
Homology modeling of human Toll-like receptors TLR7, 8, and 9 ligand-binding domains
Tiandi Wei et al.
PROTEIN SCIENCE (2009)
CL097, A TLR7/8 LIGAND, INHIBITS TLR-4-DEPENDENT ACTIVATION OF IRAK-M AND BCL-3 EXPRESSION
Branka Petricevic et al.
SHOCK (2009)
The antiviral activity of toll-like receptor 7 and 7/8 agonists
Richard L. Miller et al.
DRUG NEWS & PERSPECTIVES (2008)
The generalized Born/volume integral implicit solvent model: Estimation of the free energy of hydration using London dispersion instead of atomic surface area
Paul Labute
JOURNAL OF COMPUTATIONAL CHEMISTRY (2008)
TLR7 and TLR8 as targets in cancer therapy
M. P. Schoen et al.
ONCOGENE (2008)
The use of TLR7 and TLR8 ligands for the enhancement of cancer immunotherapy
Evelien L. J. M. Smits et al.
ONCOLOGIST (2008)
A semiempirical free energy force field with charge-based desolvation
Ruth Huey et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2007)
Nucleic acid agonists for toll-like receptor 7 are defined by the presence of uridine ribonucleotides
Sandra S. Diebold et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2006)
Innate sensing of self and non-self RNAs by Toll-like receptors
M Sioud
TRENDS IN MOLECULAR MEDICINE (2006)
Advances in homology protein structure modeling
Zhexin Xiang
CURRENT PROTEIN & PEPTIDE SCIENCE (2006)
Human cardiac inflammatory responses triggered by Coxsackie B viruses are mainly Toll-like receptor (TLR) 8-dependent
K Triantafilou et al.
CELLULAR MICROBIOLOGY (2005)
Toll-like receptors in innate immunity
K Takeda et al.
INTERNATIONAL IMMUNOLOGY (2005)
Current and potential uses of imiquimod
YC Chang et al.
SOUTHERN MEDICAL JOURNAL (2005)
Recognition of single-stranded RNA viruses by Toll-like receptor 7
JM Lund et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Development and testing of a general amber force field
JM Wang et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2004)
Exploring protein native states and large-scale conformational changes with a modified generalized born model
A Onufriev et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2004)
Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: Activation of Toll-like receptor 7
J Lee et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
The toll-like receptor 7 (TLR7)-specific stimulus loxoribine uncovers a strong relationship within the TLR7, 8 and 9 subfamily
F Heil et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2003)
Effective Born radii in the generalized Born approximation: The importance of being perfect
A Onufriev et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2002)
Parametrization of a generalized born/solvent-accessible surface area model and applications to the simulation of protein dynamics
JA Zhu et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2002)
Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway
H Hemmi et al.
NATURE IMMUNOLOGY (2002)
Calculating structures and free energies of complex molecules: Combining molecular mechanics and continuum models
PA Kollman et al.
ACCOUNTS OF CHEMICAL RESEARCH (2000)
分享论文
