期刊
MOLECULES
卷 21, 期 1, 页码 -出版社
MDPI AG
DOI: 10.3390/molecules21010045
关键词
Schmidt reaction; aldehydes; nitriles; HFIP
资金
- University of Kansas
The Schmidt reaction of aromatic aldehydes using a substoichiometric amount (40 mol %) of triflic acid is described. Low catalyst loading was enabled by a strong hydrogen-bond-donating solvent hexafluoro-2-propanol (HFIP). This improved protocol tolerates a broad scope of aldehydes with diverse functional groups and the corresponding nitriles were obtained in good to high yields without the need for aqueous work up.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据