期刊
MOLECULES
卷 20, 期 7, 页码 12436-12449出版社
MDPI
DOI: 10.3390/molecules200712436
关键词
chromone-tetrazoles; Ugi-azide reaction; antimicrobial activity; pathogenic protozoa; pathogenic bacteria; pathogenic fungi; tropical diseases
资金
- CONACyT [CB-2011-166747-Q, 370144/304476]
- Secretaria de Educacion Publica-Programa de Mejoramiento del Profesorado (SEP-PROMEP) [promep-103.5/13/5669]
- Laboratorio Nacional de Caracterizacion de Propiedades Fisicoquimicas y Estructura Molecular (CONACYT) [123732]
In vitro studies to fourteen previously synthesized chromone-tetrazoles and four novel fluorine-containing analogs were conducted against pathogenic protozoan (Entamoeba histolytica), pathogenic bacteria (Pseudomonas aeruginosa, and Staphylococcus aureus), and human fungal pathogens (Sporothrix schenckii, Candida albicans, and Candida tropicalis), which have become in a serious health problem, mainly in tropical countries.
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