Air-Stable Bifunctional HASPO Preligands for Metal-Catalyzed Cross-Couplings and Direct C-H Bond Arylations

Progress in the use of heteroatom-substituted secondary phosphine oxides (HASPO) as bifunctional preligands in transition-metal-catalyzed cross-coupling reactions as well as C-H bond functionalizations with challenging substrates is summarized herein until July 2010.