期刊
MOLECULAR PLANT PATHOLOGY
卷 17, 期 1, 页码 55-64出版社
WILEY
DOI: 10.1111/mpp.12259
关键词
F-box; Fusarium oxysporum; MAPK pathways; virulence
资金
- Spanish Ministerio de Ciencia e Innovacion (MICINN) [BIO2013-47870, BIO2008-04479-E, EUI2009-03942]
- Junta de Andalucia [BIO-3847]
- Marie Curie Initial Training Network ARIADNE [FP7-PEOPLE-ITN-237936]
- Spanish Ministerio de Educacion y Ciencia
F-box proteins determine substrate specificity of the ubiquitin-proteasome system. Previous work has demonstrated that the F-box protein Fbp1, a component of the SCFFbp1 E3 ligase complex, is essential for invasive growth and virulence of the fungal plant pathogen Fusarium oxysporum. Here, we show that, in addition to invasive growth, Fbp1 also contributes to vegetative hyphal fusion and fungal adhesion to tomato roots. All of these functions have been shown previously to require the mitogen-activated protein kinase (MAPK) Fmk1. We found that Fbp1 is required for full phosphorylation of Fmk1, indicating that Fbp1 regulates virulence and invasive growth via the Fmk1 pathway. Moreover, the Delta fbp1 mutant is hypersensitive to sodium dodecylsulfate (SDS) and calcofluor white (CFW) and shows reduced phosphorylation levels of the cell wall integrity MAPK Mpk1 after SDS treatment. Collectively, these results suggest that Fbp1 contributes to both the invasive growth and cell wall integrity MAPK pathways of F. oxysporum.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据