期刊
INTERNATIONAL PSYCHOGERIATRICS
卷 21, 期 3, 页码 520-525出版社
CAMBRIDGE UNIV PRESS
DOI: 10.1017/S1041610209008631
关键词
dementia with Lewy bodies; eating problems; swallowing problems; extrapyramidal signs; autonomic dysfunction
Background: Eating problems occur frequently in patients with dementia, and almost half of all patients with Parkinson's disease have such problems. It has therefore been assumed that eating problems are also common in patients with dementia with Lewy bodies (DLB). However, few systematic studies have investigated eating problems in DLB patients. The aim of this study was to clarify the frequency and characteristics of eating problems in patients with DLB. Methods: We examined 29 consecutive patients with DLB and 33 with Alzheimer's disease (AD) in terms of age, sex, education, Mini-mental State Examination, clinical dementia rating (CDR), neuropsychiatric inventory (NPI), Unified Parkinson disease rating scale (UPDRS), fluctuations in cognition, and usage of neuroleptic drugs / antiparkinsonian drugs. We employed a comprehensive questionnaire comprising 40 items and compared the scores between the two groups. Results: DLB patients showed significantly higher scores than AD patients for difficulty in swallowing foods, difficulty in swallowing liquids, coughing or choking when swallowing, taking a long time to swallow, suffering from sputum, loss of appetite, need watching or help, and constipation. Only the UPDRS score significantly affected the scores for difficulty in swallowing foods, taking a long time to swallow and needs watching or help score, whereas only the NPI score affected the score for loss of appetite. The scores for UPDRS, NPI and CDR significantly affected the scores for difficulty in swallowing liquids. No significant independent variables affected the scores for coughing or choking when swallowing, suffering from sputum and constipation. Conclusion: Although DLB patients show many eating problems, the causes of each problem vary, and the severity of dementia or Parkinsonism is not the only determinant.
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