Blood biomarkers in stroke: research and clinical practice

Blood biomarkers may have applications in stroke diagnosis, outcome prediction, or treatment. In this article, we provide a focused review on some of the methodological challenges and potential developments of biomarkers in stroke. We review the approaches to the development of a diagnostic blood marker: a candidate marker approach, marker panels, and omics. Then we examined the role of blood markers to predict recurrent stroke and treatment response in stroke.