期刊
INTERNATIONAL JOURNAL OF STD & AIDS
卷 26, 期 12, 页码 893-902出版社
SAGE PUBLICATIONS LTD
DOI: 10.1177/0956462414563626
关键词
Human papillomavirus; HPV; women; vaccine; knowledge; attitudes; brief intervention; Cambodia; female sex workers; HIV; sexually transmitted infection; cervical cancer; prevention
资金
- U.S. National Institutes of Health, National Institute of Nursing Research [R01NR010995]
- Canadian Institutes of Health Research
- Australian National Health and Medical Research Council (NHMRC) Research Fellowships
- Australian Government Department of Health and Ageing
- UCSF Global Health Sciences Masters' program
Human papillomavirus is a common sexually transmitted infection and the causative agent for cervical cancer, a frequently occurring malignant disease among women in developing countries. We assessed human papillomavirus awareness prior to the delivery of a brief information and education intervention, and human papillomavirus vaccine provision to female entertainment and sex workers (N=220). At baseline, only 23.6% of women had heard of human papillomavirus. Following the educational intervention, 90% answered all the human papillomavirus knowledge questions correctly. Of 192 participants attending the first quarterly cohort visit where vaccine was offered, 149 (78%) were eligible for vaccination; HIV-positive (n=32) and pregnant (n=11) women were excluded. Acceptance of vaccine among eligible women was universal, and 79.2% completed the three-dose vaccination series. Women who reported use of amphetamine-type stimulants had significantly and independently lower odds of vaccine completion (adjusted odds ratio [AOR] 0.24; 95% confidence interval [CI] 0.08, 0.69). New pregnancies also had an impact on vaccine completion: 5.4% (8/149 5.4%) who started the series had to stop due to new pregnancy. Results demonstrate the effectiveness of a simple education intervention designed to increase human papillomavirus knowledge and the feasibility of successful human papillomavirus vaccine in a population that is often difficult to engage in preventive health care.
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