期刊
INTERNATIONAL JOURNAL OF STD & AIDS
卷 21, 期 12, 页码 814-818出版社
SAGE PUBLICATIONS LTD
DOI: 10.1258/ijsa.2010.010168
关键词
HIV; HAART; echocardiography; zidovudine; diastolic dysfunction
资金
- National Key Technologies R&D Program for the 11th Five-year Plan [2008ZX10001-006]
- Ministry of Health Clinical HIV/AIDS Research
- Beijing Science and Technology [D0906003040491]
This study assessed cardiac diastolic dysfunction (DD) in HIV-infected subjects without cardiovascular symptoms in China. Eighty-four HIV-infected patients without cardiovascular symptoms were recruited and compared with 30 HIV-negative control subjects. Cardiac DD was evaluated using echocardiography including tissue Doppler imaging. DD was detected in 47.6% of AIDS patients and 42.8% of HIV-positive patients, which was significantly higher than in HIV-negative controls. After logistic regression analysis, HIV infection was independently correlated with cardiac DD (P < 0.05). Among HIV-positive subjects, logistic regression analysis showed that zidovudine exposure was associated with higher prevalence of DD (P < 0.05). Asymptomatic cardiac DD was observed frequently in HIV-infected subjects. HIV infection itself and zidovudine exposure were correlated with a higher prevalence of cardiac DD.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据