期刊
MOLECULAR IMMUNOLOGY
卷 63, 期 1, 页码 3-8出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.molimm.2014.02.007
关键词
Mast cell; Eosinophilic granular cell; Teleost; Fish; Disease
资金
- COST Action of European Community [BM1007]
The growing interest in fish models could raise an opportunity to better understand mast cell functions. The piscine mast cell, also known as eosinophilic granular cell, originates from haematopoietic organs, migrates to sites of maturation, and increases in injured tissues. Although there has been confusion arising from the different distribution in fish species and morphological and staining properties, there is a general agreement that the main functional roles, as those exploited in immunity, are quite similar. The aim of this review is to mainly focus on the roles of mast cells in teleost fish disease and in fish models of human diseases, with the attempt to give a comprehensive picture of their role in piscine immune function and their relationship to other immune system cells. (C) 2014 Elsevier Ltd. All rights reserved.
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