期刊
INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES
卷 21, 期 8, 页码 1478-1486出版社
WILEY
DOI: 10.1111/1756-185X.13344
关键词
genetic factor; major histocompatibility complex; systemic sclerosis
类别
资金
- Tehran University of Medical Sciences [93-04-41-27689]
Systemic sclerosis (SSc) is a chronic autoimmune disease of the connective tissues of unknown etiology, characterized mainly by fibrosis of the skin, vascular abnormalities, and systemic involvement of other organs, such as gastrointestinal tract, kidneys, lungs, and heart. SSc has been associated with a complex etiology with the involvement of both environmental and genetic factors in the onset and outcome of the disease. Although several major histocompatibility complex (MHC) and non-MHC genes have been associated with the disease risk, there are several questions to answer. This article's purpose was to provide an extensive overview of the identified genetic factors in the etiopathogenesis of SSc.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据