期刊
MOLECULAR DIVERSITY
卷 19, 期 4, 页码 703-708出版社
SPRINGER
DOI: 10.1007/s11030-015-9601-7
关键词
N-Arylation; Carbodiimides; Copper-catalyzed; Biguanides; Tetramethylguanidine
An efficient and experimentally simple copper-catalyzed carbon-nitrogen bond formation for the synthesis of -arylated biguanides starting from aryl halides, carbodiimides, and 1,1,3,3-tetramethylguanidine is reported. The potential diversity of this type of reaction, easily available starting materials, and commercially available low-cost catalysts are the incremental features of this methodology.
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