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Andrew C. Hsieh et al.
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Andrei V. Budanov et al.
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Core signaling pathways in human pancreatic cancers revealed by global genomic analyses
Sian Jones et al.
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Chung-Han Lee et al.
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Reuben J. Shaw et al.
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ZH Feng et al.
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K Inoki et al.
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SC Abraham et al.
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