期刊
INTERNATIONAL JOURNAL OF PSYCHOPHYSIOLOGY
卷 87, 期 1, 页码 19-27出版社
ELSEVIER
DOI: 10.1016/j.ijpsycho.2012.10.012
关键词
Anxiety; Psychopathology; Heart rate; Heart rate variability
资金
- Studienstiftung des Deutschen Volkes [German National Academic Foundation], Germany (Pittig)
- Deutscher Akademischer Austauschdienst [German Academic Exchange Service], Germany (Pittig)
- University of Colorado at Boulder (Arch)
It remains unclear if diminished high frequency heart rate variability (HF-HRV) can be found across anxiety disorders. HF-HRV and heart rate (HR) were examined in panic (PD), generalized anxiety (GAD), social anxiety (SAD), and obsessive-compulsive disorder (OCD) relative to healthy controls at baseline and during anxiety stressors. All disorders evidenced diminished baseline HF-HRV relative to controls. Baseline HRV differences were maintained throughout relaxation. For hyperventilation, PD and GAD demonstrated greater HR than controls. Psychotropic medication did not account for HF-HRV differences except in OCD. Age and sex evidenced multiple main effects. Findings suggest that low baseline HF-HRV represents a common index for inhibitory deficits across PD, GAD, and SAD, which is consistent with the notion of autonomic inflexibility in anxiety disorders. Elevated HR responses to hyperventilation, however, are specific to PD and GAD. (C) 2012 Elsevier B.V. All rights reserved.
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