期刊
MOLECULAR BIOLOGY AND EVOLUTION
卷 33, 期 2, 页码 305-310出版社
OXFORD UNIV PRESS
DOI: 10.1093/molbev/msv249
关键词
Archaea; horizontal gene transfer; ancestral genome reconstruction
资金
- Ancestrome Project [ANR-10-BINF-01-01]
In a recent article, Nelson-Sathi et al. (NS) report that the origins of major archaeal lineages (MAL) correspond to massive group-specific gene acquisitions via HGT from bacteria (Nelson-Sathi et al. 2015. Origins of major archaeal clades correspond to gene acquisitions from bacteria. Nature 517(7532):77-80.). If correct, this would have fundamental implications for the process of diversification in microbes. However, a reexamination of these data and results shows that the methodology used by NS systematically inflates the number of genes acquired at the root of each MAL, and incorrectly assumes bacterial origins for these genes. A reanalysis of their data with appropriate phylogenetic models accounting for the dynamics of gene gain and loss between lineages supports the continuous acquisition of genes over long periods in the evolution of Archaea.
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