期刊
INTERNATIONAL JOURNAL OF PHARMACEUTICS
卷 381, 期 1, 页码 1-18出版社
ELSEVIER
DOI: 10.1016/j.ijpharm.2009.07.033
关键词
Poly(epsilon-caprolactone)-poly(ethylene glycol) copolymer Microparticles; Nanoparticles; Polymeric drug delivery systems; Hydrogels
资金
- National High-Tech Project (863 Project) [2007AA021902]
- National Natural Science Foundation [NSFC20704027]
- Specialized Research Fund for the Doctoral Program of Higher Education (SRFDP) [200806100065]
- New Century Excellent Talents in University [NCET-08-0371]
- Chinese Key Basic Research Program [2004CB518807]
Poly(epsilon-caprolactone)-poly(ethylene glycol) (PCL-PEG) copolymers are important synthetic biomedical materials with amphiphilicity, controlled biodegradability, and great biocompatibility. They have great potential application in the fields of nanotechnology, tissue engineering, pharmaceutics, and medicinal chemistry. This review introduced several aspects of PCL-PEG copolymers, including synthetic chemistry, PCL-PEG micro/nanoparticles, PCL-PEG hydrogels, and physicochemical and toxicological properties. (C) 2009 Elsevier B.V. All rights reserved.
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