期刊
INTERNATIONAL JOURNAL OF PHARMACEUTICS
卷 364, 期 2, 页码 176-187出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.ijpharm.2008.05.014
关键词
Supercritical fluids; Micronization; Coating; Foaming; Cyclodextrin; Tissue engineering; Extrusion; Liposomes; Sterilization; Solvent removal
The present work focuses on some applications of supercritical fluids in the pharmaceutical field, provides a critical review of the most recent advances and aims to give a vision on the future of this technology. In particular, processes such as particle and crystal engineering, formation of cyclodextrin complexes, coating, foaming and tissue engineering, extrusion, production of liposomes, formulation of biotechnological compounds, sterilization and solvent removal are described and discussed. (c) 2008 Elsevier B.V. All rights reserved.
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