期刊
INTERNATIONAL JOURNAL OF ORAL & MAXILLOFACIAL IMPLANTS
卷 28, 期 1, 页码 51-56出版社
QUINTESSENCE PUBLISHING CO INC
DOI: 10.11607/jomi.2667
关键词
bone regeneration; biphasic calcium phosphate; human histology; sinus augmentation
资金
- Ministry of Education, University and Research (M.I.U.R.), Rome, Italy
Purpose: To evaluate the clinical and histologic aspects of bone formation in maxillary sinus augmentation using macroporous biphasic calcium phosphate (MBCP) comprising hydroxyapatite/tricalcium phosphate (HA/TCP) 60/40 as bone-grafting material. Materials and Methods: A total of 10 patients and 12 sinuses grafted with MBCP in two-stage sinus augmentation were included in the present study. After a healing period of 6 months, bone core biopsies were harvested during implant insertion and evaluated under light microscopy. Results: The histologic examination showed that the MBCP particles were in close contact with new bone in all biopsies. Histomorphometric evaluation demonstrated that newly formed bone constituted 28.3% +/- 2.7%, residual grafted material 27.3% +/- 1.2%, and marrow spaces 45.9% +/- 1.9%. Conclusions: Histologic investigation showed that the MBCP grafted particles were embedded and integrated in the newly formed bone; this bone was in close and tight contact with the biomaterial particles. Data from the preliminary results demonstrated that MBCP is a biocompatible and osteoconductive material that can be successfully used as a grafting material for sinus floor augmentation.
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