4.5 Article Proceedings Paper

Individual differences in the neurophysiology of reward and the obesity epidemic

期刊

INTERNATIONAL JOURNAL OF OBESITY
卷 33, 期 -, 页码 S44-S48

出版社

NATURE PUBLISHING GROUP
DOI: 10.1038/ijo.2009.71

关键词

amygdale; insula; dorsal striatum; prefrontal cortex; feeding

资金

  1. NIDA NIH HHS [R03 DA022292, R03 DA022292-01] Funding Source: Medline
  2. NATIONAL INSTITUTE ON DRUG ABUSE [R03DA022292] Funding Source: NIH RePORTER

向作者/读者索取更多资源

The obesity epidemic has unfolded in a matter of decades, not millennia, and therefore cannot be attributed to a drift in the genome. Rather, the temporal characteristics of the epidemic more closely track environmental and lifestyle changes, such as reduced physical activity, increased availability of palatable and energy-dense foods and drinks, and increased acceptance of eating outside of meal time (among others). One important observation is that not everyone is becoming obese. This suggests that individual factors interact with recent environmental changes to predispose some to overeat. One hypothesis that has been gaining traction in the neuroscience community is that individual differences in the neural encoding of foods may predispose some to overeat in the presence of a surplus of energy-dense, palatable foods and drinks. The aim of this review is to highlight several possible ways by which individual differences in the neurophysiology of food reward may lead to overeating. International Journal of Obesity (2009) 33, S44-S48; doi: 10.1038/ijo.2009.71

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