期刊
INTERNATIONAL JOURNAL OF NON-LINEAR MECHANICS
卷 56, 期 -, 页码 105-114出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.ijnonlinmec.2013.03.005
关键词
Finite deformations; Active tension; Pseudo-elasticity; Transverse isotropy; Muscle tissue
类别
资金
- King Abdullah University of Science and Technology (KAUST) [KUK-C1-013-04]
- National Science Foundation IGERT Grant [DGE-1144591]
Recent advances in engineered muscle tissue attached to a synthetic substrate motivate the development of appropriate constitutive and numerical models. Applications of active materials can be expanded by using robust, non-mammalian muscle cells, such as those of Manduca sexta. In this study, we propose a model to assist in the analysis of biohybrid constructs by generalizing a recently proposed constitutive law for Manduca muscle tissue. The continuum model accounts (i) for the stimulation of muscle fibers by introducing multiple stress-free reference configurations for the active and passive states and (ii) for the hysteretic response by specifying a pseudo-elastic energy function. A simple example representing uniaxial loading-unloading is used to validate and verify the characteristics of the model. Then, based on experimental data of muscular thin films, a more complex case shows the qualitative potential of Manduca muscle tissue in active biohybrid constructs. (C) 2013 Elsevier Ltd. All rights reserved.
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