期刊
INTERNATIONAL JOURNAL OF NEUROSCIENCE
卷 123, 期 10, 页码 741-742出版社
INFORMA HEALTHCARE
DOI: 10.3109/00207454.2013.797903
关键词
levodopa; dyskinesias; estrogen therapy; Parkinson's disease; transgender therapy
Estrogen has been implicated in controlling the pathogenesis and symptoms of Parkinson's disease (PD) in women. Here, we report a 53-year-old male with PD who underwent estrogen therapy with estradiol (E2). Within a month, he exhibited increased dyskinesias. His medication was reduced by 35% from a levodopa equivalent dose (LED) of 820-535 over three months, which overall improved his motor fluctuations and dyskinesias. Therefore, E2 therapy could have therapeutic potential in males with PD.
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