期刊
INTERNATIONAL JOURNAL OF NEUROSCIENCE
卷 121, 期 4, 页码 218-223出版社
TAYLOR & FRANCIS LTD
DOI: 10.3109/00207454.2010.546537
关键词
Cardiovascular fitness; cognitive functioning; exercise; mild cognitive impairment; neuropsychology; older adults
资金
- National Institutes of Health [DK075119, HL089311]
Exercise has been shown to have positive effects on the brain and cognition in healthy older adults, though no study has directly examined possible cognitive benefits of formal exercise programs in persons with mild cognitive impairment (MCI) living in structured facilities. Thirty-one participants completed neuropsychological testing and measures of cardiovascular fitness at baseline and after 6 months of a structured exercise program that included aerobic and resistance training. While exercise improved cardiovascular fitness in persons with MCI, there was no improvement in cognitive function. Rather, MCI patients in this sample declined in performance on several tests sensitive to Alzheimer's disease. Examined in the context of past work, it appears exercise may be beneficial prior to the onset of MCI, though less helpful after its onset.
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