相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Ras and Rap1: A tale of two GTPases
Seema Shah et al.
SEMINARS IN CANCER BIOLOGY (2019)
Geranylgeraniol Prevents Statin-Dependent Myotoxicity in C2C12 Muscle Cells through RAP1 GTPase Prenylation and Cytoprotective Autophagy
Anna Jaskiewicz et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2018)
Phosphorylation of Rap1 by cAMP-dependent Protein Kinase (PKA) Creates a Binding Site for KSR to Sustain ERK Activation by cAMP
Maho Takahashi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
Protein post-translational modifications: &ITIn silico&IT prediction tools and molecular modeling
Martina Audagnotto et al.
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL (2017)
Rap1 in endothelial biology
Magdalena Chrzanowska-Wodnicka
CURRENT OPINION IN HEMATOLOGY (2017)
Mitophagy is required for mitochondrial biogenesis and myogenic differentiation of C2C12 myoblasts
Jon Sin et al.
AUTOPHAGY (2016)
The Fourth International Symposium on Genetic Disorders of the Ras/MAPK pathway
David A. Stevenson et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART A (2016)
cAMP-dependent protein kinase (PKA) complexes probed by complementary differential scanning fluorimetry and ion mobility-mass spectrometry
Dominic P. Byrne et al.
BIOCHEMICAL JOURNAL (2016)
Differences in the Phosphorylation-Dependent Regulation of Prenylation of Rap1A and Rap1B
Jessica M. Wilson et al.
JOURNAL OF MOLECULAR BIOLOGY (2016)
Structural Basis of Dimeric Rasip1 RA Domain Recognition of the Ras Subfamily of GTP-Binding Proteins
Alexandre R. Gingras et al.
STRUCTURE (2016)
The structure and conformational switching of Rap1B
Hiroki Noguchi et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2015)
RAP1-mediated MEK/ERK pathway defects in Kabuki syndrome
Nina Boegershausen et al.
JOURNAL OF CLINICAL INVESTIGATION (2015)
MiR-203 down-regulates Rap1A and suppresses cell proliferation, adhesion and invasion in prostate cancer
Jun Xiang et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2015)
Rap1 Spatially Controls ArhGAP29 To Inhibit Rho Signaling during Endothelial Barrier Regulation
A. Post et al.
MOLECULAR AND CELLULAR BIOLOGY (2015)
A novel pathway of rapid TLR-triggered activation of integrin-dependent leukocyte adhesion that requires Rap1 GTPase
Kyoung-Jin Chung et al.
MOLECULAR BIOLOGY OF THE CELL (2014)
Rap1 signaling in endothelial barrier control
Willem-Jan Pannekoek et al.
CELL ADHESION & MIGRATION (2014)
Regulation of vascular endothelial junction stability and remodeling through Rap1-Rasip1 signaling
Christopher W. Wilson et al.
CELL ADHESION & MIGRATION (2014)
Anoikis molecular pathways and its role in cancer progression
Paolo Paoli et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2013)
Unmasking Kabuki syndrome
N. Boegershausen et al.
CLINICAL GENETICS (2013)
Distinct functions for Rap1 signaling in vascular morphogenesis and dysfunction
Magdalena Chrzanowska-Wodnicka
EXPERIMENTAL CELL RESEARCH (2013)
Protein Kinase A-dependent Phosphorylation of Rap1 Regulates Its Membrane Localization and Cell Migration
Maho Takahashi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Getting Leukocytes to the Site of Inflammation
W. A. Muller
VETERINARY PATHOLOGY (2013)
Prenyltransferase inhibitors: treating human ailments from cancer to parasitic infections
Joshua D. Ochocki et al.
MEDCHEMCOMM (2013)
Rap1a deficiency modifies cytokine responses and MAPK-signaling in vitro and impairs the in vivo inflammatory response
Annette Dorn et al.
CELLULAR IMMUNOLOGY (2012)
Functions of p120ctn isoforms in cell-cell adhesion and intracellular signaling
Tim Pieters et al.
FRONTIERS IN BIOSCIENCE-LANDMARK (2012)
Integrins and cadherins join forces to form adhesive networks
Gregory F. Weber et al.
JOURNAL OF CELL SCIENCE (2011)
Breast cancer cell migration is regulated through junctional adhesion molecule-A-mediated activation of Rap1 GTPase
Elaine A. McSherry et al.
BREAST CANCER RESEARCH (2011)
Preventing the Activation or Cycling of the Rap1 GTPase Alters Adhesion and Cytoskeletal Dynamics and Blocks Metastatic Melanoma Cell Extravasation into the Lungs
Spencer A. Freeman et al.
CANCER RESEARCH (2010)
Rac and Rho GTPases in cancer cell motility control
Matteo Parri et al.
CELL COMMUNICATION AND SIGNALING (2010)
Rap1 Promotes Multiple Pancreatic Islet Cell Functions and Signals through Mammalian Target of Rapamycin Complex 1 to Enhance Proliferation
Patrick Kelly et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Splice Variants of SmgGDS Control Small GTPase Prenylation and Membrane Localization
Tracy J. Berg et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
p120ctn and P-Cadherin but Not E-Cadherin Regulate Cell Motility and Invasion of DU145 Prostate Cancer Cells
Sandra Kuemper et al.
PLOS ONE (2010)
Regulation of angiogenesis by a small GTPase Rap1
Magdalena Chrzanowska-Wodnicka
VASCULAR PHARMACOLOGY (2010)
Activation of Rap1 Promotes Prostate Cancer Metastasis
Candice L. Bailey et al.
CANCER RESEARCH (2009)
Control of cell adhesion dynamics by Rap1 signaling
Benjamin Boettner et al.
CURRENT OPINION IN CELL BIOLOGY (2009)
Specificity in Ras and Rap Signaling
Judith H. Raaijmakers et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
RIAM Activates Integrins by Linking Talin to Ras GTPase Membrane-targeting Sequences
Ho-Sup Lee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
The TSC1-TSC2 complex: a molecular switchboard controlling cell growth
Jingxiang Huang et al.
BIOCHEMICAL JOURNAL (2008)
Ras oncogenes: split personalities
Antoine E. Karnoub et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
KRIT-1/CCM1 is a Rap1 effector that regulates endothelial cell-cell junctions
Angela Glading et al.
JOURNAL OF CELL BIOLOGY (2007)
Role of GTPases in ribosome assembly
Katrin Karbstein
BIOPOLYMERS (2007)
IQGAP1 binds Rap1 and modulates its activity
Ha-Won Jeong et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
GEFs and GAPs: Critical elements in the control of small G proteins
Johannes L. Bos et al.
CELL (2007)
Rap1 integrates tissue polarity, lumen formation, and tumorigenic potential in human breast epithelial cells
Masahiko Itoh et al.
CANCER RESEARCH (2007)
A Rap GTPase interactor, RADIL, mediates migration of neural crest precursors
Gromoslaw A. Smolen et al.
GENES & DEVELOPMENT (2007)
Muscle stem cells in development, regeneration, and disease
Xiaozhong Shi et al.
GENES & DEVELOPMENT (2006)
Statin therapy and autoimmune disease: from protein prenylation to immunomodulation
J Greenwood et al.
NATURE REVIEWS IMMUNOLOGY (2006)
ARAP3 is essential for formation of lamellipodia after growth factor stimulation
S Krugmann et al.
JOURNAL OF CELL SCIENCE (2006)
Identification of a putative tumor suppressor gene Rap1GAP in pancreatic cancer
LZ Zhang et al.
CANCER RESEARCH (2006)
Activation of Rac by cadherin through the c-Src-Rap1-phosphatidylinositol 3-kinase-Vav2 pathway
T Fukuyama et al.
ONCOGENE (2006)
E-cadherin endocytosis regulates the activity of Rap1: a traffic light GTPase at the crossroads between cadherin and integrin function
F Balzac et al.
JOURNAL OF CELL SCIENCE (2005)
RA-RhoGAP, Rap-activated Rho GTPase-activating protein implicated in neurite outgrowth through Rho
T Yamada et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Targeting Ras and Rho GTPases as opportunities for cancer therapeutics
K Walker et al.
CURRENT OPINION IN GENETICS & DEVELOPMENT (2005)
Involvement of the c-Src-Crk-C3G-Rap1 signaling in the nectin-induced activation of Cdc42 and formation of adherens junctions
T Fukuyama et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Abrogation of insulin-like growth factor-I (IGF-I) and insulin action by mevalonic acid depletion - Synergy between protein prenylation and receptor glycosylation pathways
KW Siddals et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
CalDAG-GEFI integrates signaling for platelet aggregation and thrombus formation
JR Crittenden et al.
NATURE MEDICINE (2004)
Rap1 regulates E-cadherin-mediated cell-cell adhesion
LS Price et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Toll-like receptor (TLR) expression and TLR-mediated cytokine/chemokine production by human uterine epithelial cells
TM Schaefer et al.
IMMUNOLOGY (2004)
Distinct mechanisms determine the patterns of differential activation of H-Ras, N-Ras, K-Ras 4B, and M-Ras by receptors for growth factors or antigen
A Ehrhardt et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Statins induce apoptosis in rat and human myotube cultures by inhibiting protein geranylgeranylation but not ubiquinone
TE Johnson et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2004)
Rap1 promotes cell spreading by localizing Rac guanine nucleoticle exchange factors
WT Arthur et al.
JOURNAL OF CELL BIOLOGY (2004)
Rap1, a small GTP-binding protein is upregulated during arrest of proliferation in human keratinocytes
NJ D'Silva et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2003)
RAPL, a Rap1-binding molecule that mediates Rap1-induced adhesion through spatial regulation of LFA-1
K Katagiri et al.
NATURE IMMUNOLOGY (2003)
Myeloproliferative stem cell disorders by deregulated Rap1 activation in SPA-1-deficient mice
D Ishida et al.
CANCER CELL (2003)
The small GTPase Rap1 is activated by turbulence and is involved in integrin αIIbβ3-mediated cell adhesion in human megakaryocytes
KMT de Bruyn et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Role of the Rap1 GTPase in astrocyte growth regulation
AJ Apicelli et al.
GLIA (2003)
Identification of a novel phosphonocarboxylate inhibitor of Rab geranylgeranyl transferase that specifically prevents Rab prenylation in osteoclasts and macrophages
FP Coxon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Cell adhesion in tumor invasion and metastasis: loss of the glue is not enough
U Cavallaro et al.
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2001)
Coordinated regulation of Rap1 and thyroid differentiation by cyclic AMP and protein kinase A
OM Tsygankova et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
Rap1A protein interferes with various MAP kinase activating pathways in skeletal myogenic cells
V Pizon et al.
ONCOGENE (2000)
The junctional multidomain protein AF-6 is a binding partner of the Rap1A GTPase and associates with the actin cytoskeletal regulator profilin
B Boettner et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
The small GTPase, Rap1, mediates CD31-induced integrin adhesion
KA Reedquist et al.
JOURNAL OF CELL BIOLOGY (2000)
分享论文
