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The pro- and anti-inflammatory properties of the cytokine interleukin-6
Juergen Scheller et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2011)
Constitutive and LPS-regulated expression of interleukin-18 receptor beta variants in the mouse brain
Silvia Alboni et al.
BRAIN BEHAVIOR AND IMMUNITY (2011)
Upregulation of circulating IL-15 by treadmill running in healthy individuals: Is IL-15 an endocrine mediator of the beneficial effects of endurance exercise?
Yoshiaki Tamura et al.
ENDOCRINE JOURNAL (2011)
Source and kinetics of interleukin-6 in humans during exercise demonstrated by a minimally invasive model
Anders Dyhr Toft et al.
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY (2011)
Inflammation-Associated Interleukin-6/Signal Transducer and Activator of Transcription 3 Activation Ameliorates Alcoholic and Nonalcoholic Fatty Liver Diseases in Interleukin-10-Deficient Mice
Andrew M. Miller et al.
HEPATOLOGY (2011)
The Roles of IL-6, IL-10, and IL-1RA in Obesity and Insulin Resistance in African-Americans
Bashira A. Charles et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2011)
Loss of IL-15 receptor α alters the endurance, fatigability, and metabolic characteristics of mouse fast skeletal muscles
Emidio E. Pistilli et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Interleukin-6 Regulates the Expression of Hypothalamic Neuropeptides Involved in Body Weight in a Gender-Dependent Way
R. M. Senaris et al.
JOURNAL OF NEUROENDOCRINOLOGY (2011)
Alternatively activated macrophages produce catecholamines to sustain adaptive thermogenesis
Khoa D. Nguyen et al.
NATURE (2011)
Brown adipose tissue activity controls triglyceride clearance
Alexander Bartelt et al.
NATURE MEDICINE (2011)
Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells
Helga Ellingsgaard et al.
NATURE MEDICINE (2011)
Interleukin-15, IL-15 Receptor-Alpha, and Obesity: Concordance of Laboratory Animal and Human Genetic Studies
LeBris S. Quinn et al.
JOURNAL OF OBESITY (2011)
Central administration of interleukin-4 exacerbates hypothalamic inflammation and weight gain during high-fat feeding
Shinsuke Oh-I et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2010)
Interleukin-6 Signaling in Liver-Parenchymal Cells Suppresses Hepatic Inflammation and Improves Systemic Insulin Action
F. Thomas Wunderlich et al.
CELL METABOLISM (2010)
Interleukin-33 Induces Protective Effects in Adipose Tissue Inflammation During Obesity in Mice
Ashley M. Miller et al.
CIRCULATION RESEARCH (2010)
Interleukin-6-deficient mice develop hepatic inflammation and systemic insulin resistance
V. B. Matthews et al.
DIABETOLOGIA (2010)
Inducible Lineage Tracing of Pax7-Descendant Cells Reveals Embryonic Origin of Adult Satellite Cells
Christoph Lepper et al.
GENESIS (2010)
IL-6: from its discovery to clinical applications
Tadamitsu Kishimoto
INTERNATIONAL IMMUNOLOGY (2010)
IL-15 Receptor Deletion Results in Circadian Changes of Locomotor and Metabolic Activity
Yi He et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2010)
Plasma Cytokine Levels in a Population-Based Study: Relation to Age and Ethnicity
Raymond P. Stowe et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2010)
Interleukin-15 Contributes to the Regulation of Murine Adipose Tissue and Human Adipocytes
Nicole G. Barra et al.
OBESITY (2010)
IL-4/STAT6 immune axis regulates peripheral nutrient metabolism and insulin sensitivity
Roberto R. Ricardo-Gonzalez et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
IL-6 and IL-10 Anti-Inflammatory Activity Links Exercise to Hypothalamic Insulin and Leptin Sensitivity through IKKβ and ER Stress Inhibition
Eduardo R. Ropelle et al.
PLOS BIOLOGY (2010)
The regulation of IL-10 production by immune cells
Margarida Saraiva et al.
NATURE REVIEWS IMMUNOLOGY (2010)
Oversecretion of interleukin-15 from skeletal muscle reduces adiposity
LeBris S. Quinn et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2009)
IL-33, a recently identified interleukin-1 gene family member, is expressed in human adipocytes
I. Stuart Wood et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2009)
Loss of Kupffer cells in diet-induced obesity is associated with increased hepatic steatosis, STAT3 signaling, and further decreases in insulin signaling
Alicia H. Clementi et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2009)
Interleukin-10 Prevents Diet-Induced Insulin Resistance by Attenuating Macrophage and Cytokine Response in Skeletal Muscle
Eun-Gyoung Hong et al.
DIABETES (2009)
High Incidence of Metabolically Active Brown Adipose Tissue in Healthy Adult Humans Effects of Cold Exposure and Adiposity
Masayuki Saito et al.
DIABETES (2009)
Therapeutic potential of interleukin-15: a myokine involved in muscle wasting and adiposity
Josep M. Argiles et al.
DRUG DISCOVERY TODAY (2009)
Hormone therapy attenuates exercise-induced skeletal muscle damage in postmenopausal women
Christina M. Dieli-Conwright et al.
JOURNAL OF APPLIED PHYSIOLOGY (2009)
Interleukin-6 Gene Knockout Influences Energy Balance Regulating Peptides in the Hypothalamic Paraventricular and Supraoptic Nuclei
A. Benrick et al.
JOURNAL OF NEUROENDOCRINOLOGY (2009)
Initiation of myoblast to brown fat switch by a PRDM16-C/EBP-β transcriptional complex
Shingo Kajimura et al.
NATURE (2009)
Identification and Importance of Brown Adipose Tissue in Adult Humans.
Aaron M. Cypess et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
Thermogenically competent nonadrenergic recruitment in brown preadipocytes by a PPARγ agonist
Natasa Petrovic et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2008)
Phenotypic Switching of Adipose Tissue Macrophages With Obesity Is Generated by Spatiotemporal Differences in Macrophage Subtypes
Carey N. Lumeng et al.
DIABETES (2008)
Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex
Shingo Kajimura et al.
GENES & DEVELOPMENT (2008)
Interleukin-18 resistance in patients with obesity and type 2 diabetes mellitus
G. R. C. Zilverschoon et al.
INTERNATIONAL JOURNAL OF OBESITY (2008)
The extended IL-10 superfamily: IL-10, IL-19, IL-20, IL-22, IL-24, IL-26, IL-28, and IL-29
Scott Commins et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2008)
Association between Interleukin-15 and Obesity: Interleukin-15 as a Potential Regulator of Fat Mass
Anders Rinnov Nielsen et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2008)
Interleukin-10 is a protective factor against diet-induced insulin resistance in liver
Dennys E. Cintra et al.
JOURNAL OF HEPATOLOGY (2008)
IL-10: The master regulator of immunity to infection
Kevin N. Couper et al.
JOURNAL OF IMMUNOLOGY (2008)
PRDM16 controls a brown fat/skeletal muscle switch
Patrick Seale et al.
NATURE (2008)
New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure
Yu-Hua Tseng et al.
NATURE (2008)
Effects of IL-15 on rat brown adipose tissue:: Uncoupling proteins and PPARs
Vanessa Almendro et al.
OBESITY (2008)
Intracellular interaction of interleukin-15 with its receptor α during production leads to mutual stabilization and increased bioactivity
Cristina Bergamaschi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Expression of interleukin-15 in human skeletal muscle - effect of exercise and muscle fibre type composition
Anders Rinnov Nielsen et al.
JOURNAL OF PHYSIOLOGY-LONDON (2007)
The transcriptional coactivator peroxisome proliferator-activated receptor (PPAR)γ coactivator-1α and the nuclear receptor PPARα control the expression of glycerol kinase and metabolism genes independently of PPARγ activation in human white adipocytes
Anne Mazzucotelli et al.
DIABETES (2007)
The IL-4/IL-13/Stat6 signalling pathway promotes luminal mammary epithelial cell development
Walid T. Khaled et al.
DEVELOPMENT (2007)
Transcriptional control of brown fat determination by PRDM16
Patrick Seale et al.
CELL METABOLISM (2007)
Interleukin-18 controls energy homeostasis by suppressing appetite and feed efficiency
Eric P. Zorriila et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Myogenic gene expression signature establishes that brown and white adipocytes originate from distinct cell lineages
James A. Timmons et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Maximal β3-adrenergic regulation of lipolysis involves Src and epidermal growth factor receptor-dependent ERK1/2 activation
Jacques Robidoux et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Interleukin-6 regulation of AMP-activated protein kinase - Potential role in the systemic response to exercise and prevention of the metabolic syndrome
Neil B. Ruderman et al.
DIABETES (2006)
Carboxyatractyloside effects on brown-fat mitochondria imply that the adenine nucleotide translocator isoforms ANT1 and ANT2 may be responsible for basal and fatty-acid-induced uncoupling respectively
Irina G. Shabalina et al.
BIOCHEMICAL JOURNAL (2006)
Endogenous interleukin-10 protects against hepatic steatosis but does not improve insulin sensitivity during high-fat feeding in mice
Marion A. M. den Boer et al.
ENDOCRINOLOGY (2006)
Deficiency of interleukin-18 in mice leads to hyperphagia, obesity and insulin resistance
MG Netea et al.
NATURE MEDICINE (2006)
Reduced stress- and cold-induced increase in energy expenditure in interleukin-6-deficient mice
Ingrid Wernstedt et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2006)
Association of interleukin-6, C-reactive protein, interleukin-10 and adiponectin plasma concentrations with measures of obesity, insulin sensitivity and glucose metabolism
M Blüher et al.
EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES (2005)
Association between circulating adiponectin and interleukin-10 levels in android obesity:: Effects of weight loss
MR Manigrasso et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2005)
The roles of interleukin-15 receptor α:: Trans-presentation, receptor component, or both?
KS Schluns et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2005)
Interleukin-15 stimulates adiponectin secretion by 3T3-L1 adipocytes:: Evidence for a skeletal muscle-to-fat signaling pathway
LBS Quinn et al.
CELL BIOLOGY INTERNATIONAL (2005)
Elevated interleukin-18 levels are associated with the metabolic syndrome independent of obesity and insulin resistance
J Hung et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2005)
The anti-inflammatory effect of exercise
AMW Petersen et al.
JOURNAL OF APPLIED PHYSIOLOGY (2005)
Cytokines and fever
B Conti et al.
FRONTIERS IN BIOSCIENCE-LANDMARK (2004)
Differential effects of interleukin-6 and-10 on skeletal muscle and liver insulin action in vivo
HJ Kim et al.
DIABETES (2004)
p38 mitogen-activated protein kinase is the central regulator of cyclic AMP-dependent transcription of the brown fat uncoupling protein 1 gene
WH Cao et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Association of interleukin-15 protein and interleukin-15 receptor genetic variation with resistance exercise training responses
SE Riechman et al.
JOURNAL OF APPLIED PHYSIOLOGY (2004)
Differences in signaling pathways by IL-1β and IL-18
JK Lee et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Reduced exercise endurance in interleukin-6 deficient mice
J Fäldt et al.
ENDOCRINOLOGY (2004)
Brown adipose tissue: Function and physiological significance
B Cannon et al.
PHYSIOLOGICAL REVIEWS (2004)
Interleukin-6 and tumor necrosis factor-α are not increased in patients with Type 2 diabetes:: evidence that plasma interleukin-6 is related to fat mass and not insulin responsiveness
AL Carey et al.
DIABETOLOGIA (2004)
Meal modulation of circulating interleukin 18 and adiponectin concentrations in healthy subjects and in patients with type 2 diabetes mellitus
K Esposito et al.
AMERICAN JOURNAL OF CLINICAL NUTRITION (2003)
Acquirement of brown fat cell features by human white adipocytes
C Tiraby et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
β-adrenergic receptors, diet-induced thermogenesis, and obesity
BB Lowell et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Effect of weight loss and lifestyle changes on vascular inflammatory markers in obese women - A randomized trial
K Esposito et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2003)
Association of low interleukin-10 levels with the metabolic syndrome in obese women
K Esposito et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2003)
Shaping gene expression in activated and resting primary macrophages by IL-10
R Lang et al.
JOURNAL OF IMMUNOLOGY (2002)
Interleukin-6 (IL-6):: A possible neuromodulator induced by neuronal activity
E Jüttler et al.
NEUROSCIENTIST (2002)
Intracerebroventricular interleukin-6 treatment decreases body fat in rats
K Wallenius et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2002)
Low production capacity of interleukin-10 associates with the metabolic syndrome and type 2 diabetes -: The Leiden 85-plus study
E van Exel et al.
DIABETES (2002)
Interleukin-6-deficient mice develop mature-onset obesity
V Wallenius et al.
NATURE MEDICINE (2002)
Induction of uncoupling protein 1 by central interleukin-6 gene delivery is dependent on sympathetic innervation of brown adipose tissue and underlies one mechanism of body weight reduction in rats
G Li et al.
NEUROSCIENCE (2002)
C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus
AD Pradhan et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2001)
UCP1: the only protein able to mediate adaptive non-shivering thermogenesis and metabolic inefficiency
J Nedergaard et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2001)
Fatal leukemia in interleukin 15 transgenic mice follows early expansions in natural killer and memory phenotype CD8+ T cells
TA Fehniger et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2001)
Elevated levels of interleukin 6 are reduced in serum and subcutaneous adipose tissue of obese women after weight loss
JP Bastard et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2000)
Tumor necrosis factor α mediates apoptosis of brown adipocytes and defective brown adipocyte function in obesity
E Nisoli et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Sex hormone levels correlate with the activity of cytokine-secreting cells in vivo
D Verthelyi et al.
IMMUNOLOGY (2000)
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