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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome
Shankar S. Iyer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Structure of IL-33 and Its Interaction with the ST2 and IL-1RAcP Receptors-Insight into Heterotrimeric IL-1 Signaling Complexes
Andreas Lingel et al.
STRUCTURE (2009)
The metastatic niche: adapting the foreign soil
Bethan Psaila et al.
NATURE REVIEWS CANCER (2009)
Interleukin-1beta and fibroblast growth factor receptor 1 cooperate to induce cyclooxygenase-2 during early mammary tumourigenesis
Johanna R. Reed et al.
BREAST CANCER RESEARCH (2009)
The IRAK-catalysed activation of the E3 ligase function of Pellino isoforms induces the Lys(63)-linked polyubiquitination of IRAK1
Alban Ordureau et al.
BIOCHEMICAL JOURNAL (2008)
Overexpression of Interleukin-1β Induces Gastric Inflammation and Cancer and Mobilizes Myeloid-Derived Suppressor Cells in Mice
Shuiping Tu et al.
CANCER CELL (2008)
Is interleukin-1 a good or bad 'guy' in tumor immunobiology and immunotherapy?
Ron N. Apte et al.
IMMUNOLOGICAL REVIEWS (2008)
The interleukin-1 receptor/Toll-like receptor superfamily: 10 years of progress
Luke A. J. O'Neill
IMMUNOLOGICAL REVIEWS (2008)
TRAF6 Autoubiquitination-Independent Activation of the NFκB and MAPK Pathways in Response to IL-1 and RANKL
Matthew C. Walsh et al.
PLOS ONE (2008)
Intracellular HMGB1 transactivates the human IL1B gene promoter through association with an Ets transcription factor PU.1
Fumihiko Mouri et al.
EUROPEAN JOURNAL OF HAEMATOLOGY (2008)
Interleukins 1β and 6 but not transforming growth factor-β are essential for the differentiation of interleukin 17-producing human T helper cells
Eva V. Acosta-Rodriguez et al.
NATURE IMMUNOLOGY (2007)
Intrathecal interleukin-10 gene therapy attenuates paclitaxel-induced mechanical allodynia and proinflammatory cytokine expression in dorsal root ganglia in rats
Annemarie Ledeboer et al.
BRAIN BEHAVIOR AND IMMUNITY (2007)
Clinical course and prognosis of smoldering (asymptomatic) multiple myeloma
Robert A. Kyle et al.
NEW ENGLAND JOURNAL OF MEDICINE (2007)
Prostaglandin E2 promotes tumor progression by inducing myeloid-derived suppressor cells
Pratima Sinha et al.
CANCER RESEARCH (2007)
Stimulation of P2 receptors causes release of IL-1β-loaded microvesicles from human dendritic cells
Cinzia Pizzirani et al.
BLOOD (2007)
Regulated intramembrane proteolysis of the interleukin-1 receptor II by α-, β-, and γ-secretase
Peer-Hendrik Kuhn et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Interleukin-1β-driven inflammation promotes the development and invasiveness of chemical carcinogen-induced tumors
Yakov Krelin et al.
CANCER RESEARCH (2007)
A crucial role for interleukin (IL)-1 in the induction of IL-17-producing T cells that mediate autoimmune encephalomyelitis
Caroline Sutton et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2006)
Evidence that hypoxia-inducible factor-1 (HIF-1) mediates transcriptional activation of interleukin-1β (IL-1β) in astrocyte cultures
Wandong Zhang et al.
JOURNAL OF NEUROIMMUNOLOGY (2006)
The interleukin-1β gene is transcribed from a poised promoter architecture in monocytes
MD Liang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Effects of micro-environment- and malignant cell-derived interleukin-1 in carcinogenesis, tumour invasiveness and tumour-host interactions
RN Apte et al.
EUROPEAN JOURNAL OF CANCER (2006)
Transcription factor YY1: structure, function, and therapeutic implications in cancer biology
S Gordon et al.
ONCOGENE (2006)
Single nucleotide polymorphisms in the human interleukin-1B gene affect transcription according to haplotype context
HM Chen et al.
HUMAN MOLECULAR GENETICS (2006)
Inflammation induces myeloid-derived suppressor cells that facilitate tumor progression
SK Bunt et al.
JOURNAL OF IMMUNOLOGY (2006)
The involvement of IL-1 in tumorigenesis, tumor invasiveness, metastasis and tumor-host interactions
Ron N. Apte et al.
CANCER AND METASTASIS REVIEWS (2006)
MyD88 mediates neutrophil recruitment initiated by IL-1R but not TLR2 activation in immunity against Staphylococcus aureus
LS Miller et al.
IMMUNITY (2006)
VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche
RN Kaplan et al.
NATURE (2005)
TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo
JH Shim et al.
GENES & DEVELOPMENT (2005)
Essential function for the kinase TAK1 in innate and adaptive immune responses
S Sato et al.
NATURE IMMUNOLOGY (2005)
Infiltration of COX-2-expressing macrophages is a prerequisite for IL-1β-induced neovascularization and tumor growth
S Nakao et al.
JOURNAL OF CLINICAL INVESTIGATION (2005)
Sequential autophosphorylation steps in the interleukin-1 receptor-associated kinase-1 regulate its availability as an adapter in interleukin-1 signaling
C Kollewe et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Hypoxic gene activation by lipopolysaccharide in macrophages:: Implication of hypoxia-inducible factor 1α
CC Blouin et al.
BLOOD (2004)
Shedding of the type II IL-1 decoy receptor requires a multifunctional aminopeptidase, aminopeptidase regulator of TNF receptor type 1 shedding
XL Cui et al.
JOURNAL OF IMMUNOLOGY (2003)
Mechanisms of caspase activation
KM Boatright et al.
CURRENT OPINION IN CELL BIOLOGY (2003)
IL-1 is required for tumor invasiveness and angiogenesis
E Voronov et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Local delivery of IL-1 alpha polymeric microspheres for the immunotherapy of an experimental fibrosarcoma
J Mullerad et al.
CANCER INVESTIGATION (2003)
Negative regulation of cytokine signaling influences inflammation
A Yoshimura et al.
CURRENT OPINION IN IMMUNOLOGY (2003)
Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes
A Mantovani et al.
TRENDS IN IMMUNOLOGY (2002)
Glucose-induced β cell production of IL-1β contributes to glucotoxicity in human pancreatic islets
K Maedler et al.
JOURNAL OF CLINICAL INVESTIGATION (2002)
Extracellular ATP and P2X7 receptors in neurodegeneration
R Le Feuvre et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2002)
Proinflammatory cytokine IL-1β promotes tumor growth of Lewis lung carcinoma by induction of angiogenic factors:: In vivo analysis of tumor-stromal interaction
Y Saijo et al.
JOURNAL OF IMMUNOLOGY (2002)
IRAK-4: A novel member of the IRAK family with the properties of an IRAK-kinase
SY Li et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Autocrine induction of the human pro-IL-1β gene promoter by IL-1β in monocytes
Y Toda et al.
JOURNAL OF IMMUNOLOGY (2002)
Rapid secretion of interleukin-1β by microvesicle shedding
A MacKenzie et al.
IMMUNITY (2001)
PU.1 and multiple IFN regulatory factor proteins synergize to mediate transcriptional activation of the human IL-1β gene
S Marecki et al.
JOURNAL OF IMMUNOLOGY (2001)
The microenvironment of the tumour-host interface
LA Liotta et al.
NATURE (2001)
The first two N-terminal immunoglobulin-like domains of soluble human IL-1 receptor type II are sufficient to bind and neutralize IL-1β
C Kollewe et al.
FEBS LETTERS (2000)
Transcriptional regulation of the human interleukin 1β gene by fibronectin:: Role of protein kinase C and activator protein 1 (AP-1)
J Roman et al.
CYTOKINE (2000)
Macrophage activation for the production of immunostimulatory cytokines by delivering interleukin 1 via biodegradable microspheres
J Mullerad et al.
CYTOKINE (2000)
Biological role of interleukin 1 receptor antagonist isoforms
WP Arend et al.
ANNALS OF THE RHEUMATIC DISEASES (2000)
The membrane form of the type IIIL-1 receptor accounts for inhibitory function
D Neumann et al.
JOURNAL OF IMMUNOLOGY (2000)
NF-IL6 (C/EBPβ) vigorously activates il1b gene expression via a Spi-1 (PU.1) protein-protein tether
ZY Yang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Tollip, a new component of the IL-1RI pathway, links IRAK to the IL-1 receptor
K Burns et al.
NATURE CELL BIOLOGY (2000)
IL-1 signaling cascade in liver cells and the involvement of a soluble form of the IL-1 receptor accessory protein
LE Jensen et al.
JOURNAL OF IMMUNOLOGY (2000)
Functional analysis of the domain structure of tumor necrosis factor-α converting enzyme
P Reddy et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Interleukin-1 polymorphisms associated with increased risk of gastric cancer
EM El-Omar et al.
NATURE (2000)
IL-18 regulates IL-1β-dependent hepatic melanoma metastasis via vascular cell adhesion molecule-1
F Vidal-Vanaclocha et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
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