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Pin1 allows for differential Tau dephosphorylation in neuronal cells
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FTDP-17 mutations compromise the ability of Tau to regulate microtubule dynamics in cells
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JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Tau becomes a more favorable substrate for GSK-3 when it is prephosphorylated by PKA in rat brain
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JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Pseudophosphorylation and glycation of tau protein enhance but do not trigger fibrillization in vitro
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JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Tau phosphorylation in neuronal cell function and dysfunction
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JOURNAL OF CELL SCIENCE (2004)
Surface-decoration of microtubules by human Tau
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JOURNAL OF MOLECULAR BIOLOGY (2004)
Dynein motors transport activated Trks to promote survival of target-dependent neurons
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NATURE NEUROSCIENCE (2004)
Aberrant Cdk5 activation by p25 triggers pathological events leading to neurodegeneration and neurofibrillary tangles
JC Cruz et al.
NEURON (2003)
Differential regulation of microtubule dynamics by three- and four-repeat tau: Implications for the onset of neurodegenerative disease
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Role of the prolyl isomerase Pin1 in protecting against age-dependent neurodegeneration
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NATURE (2003)
Cdk5 is a key factor in tau aggregation and tangle formation in vivo
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NEURON (2003)
Involvement of c-Jun N-terminal kinase in amyloid precursor protein-mediated neuronal cell death
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JOURNAL OF NEUROCHEMISTRY (2003)
Chaperones increase association of tau protein with microtubules
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Clogging of axons by tau, inhibition of axonal traffic and starvation of synapses
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NEUROBIOLOGY OF AGING (2003)
Single-molecule investigation of the interference between kinesin, tau and MAP2c
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EMBO JOURNAL (2002)
Medicine - The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
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SCIENCE (2002)
Intracellular deposition, microtubule destabilization, and transport failure: An early pathogenic cascade leading to synaptic decline
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JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2002)
Glycosaminoglycans and β-amyloid, prion and tau peptides in neurodegenerative diseases
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PEPTIDES (2002)
MAP2 and tau bind longitudinally along the outer ridges of microtubule protofilaments
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JOURNAL OF CELL BIOLOGY (2002)
High-resolution imaging demonstrates dynein-based vesicular transport of activated Trk receptors
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JOURNAL OF NEUROBIOLOGY (2002)
Colocalization and fluorescence resonance energy transfer between cdk5 and AT8 suggests a close association in pre-neurofibrillary tangles and neurofibrillary tangles
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JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2002)
Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress
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JOURNAL OF CELL BIOLOGY (2002)
Direct interaction of soluble human recombinant tau protein with Aβ 1-42 results in tau aggregation and hyperphosphorylation by tau protein kinase II
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FEBS LETTERS (2002)
Tubulin, actin, and tau protein interactions and the study of their macromolecular assemblies
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JOURNAL OF CELLULAR BIOCHEMISTRY (2002)
Specific tau phosphorylation sites correlate with severity of neuronal cytopathology in Alzheimer's disease
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ACTA NEUROPATHOLOGICA (2002)
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NEUROCHEMISTRY INTERNATIONAL (2002)
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TRENDS IN BIOCHEMICAL SCIENCES (2001)
Hyperphosphorylation induces self-assembly of τ into tangles of paired helical filaments/straight filaments
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Phosphorylated mitogen-activated protein kinase (MAPK/ERK-P), protein kinase of 38kDa (p38-P), stress-activated protein kinase (SAPK/JNK-P), and calcium/calmodulin-dependent kinase II (CaM kinase II) are differentially expressed in tau deposits in neurons and glial cells in tauopathies
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JOURNAL OF NEURAL TRANSMISSION (2001)
Activation and redistribution of c-Jun N-terminal kinase/stress activated protein kinase in degenerating neurons in Alzheimer's disease
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JOURNAL OF NEUROCHEMISTRY (2001)
Neurodegenerative tauopathies
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ANNUAL REVIEW OF NEUROSCIENCE (2001)
Axonal transport of amyloid precursor protein is mediated by direct binding to the kinesin light chain subunit of kinesin-I
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NEURON (2000)
Microtubule-affinity regulating kinase (MARK) is tightly associated with neurofibrillary tangles in Alzheimer brain: A fluorescence resonance energy transfer study
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JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2000)
Regulation and localization of tyrosine216 phosphorylation of glycogen synthase kinase-3β in cellular and animal models of neuronal degeneration
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
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IMMUNOLOGY AND CELL BIOLOGY (2000)
Casein kinase 1 delta is associated with pathological accumulation of tau in several neurodegenerative disease
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NEUROBIOLOGY OF AGING (2000)
Abnormal tau-containing filaments in neurodegenerative diseases
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JOURNAL OF STRUCTURAL BIOLOGY (2000)
Casein kinase 1 delta mRNA is upregulated in Alzheimer disease brain
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BRAIN RESEARCH (2000)
Neurotoxicity induces cleavage of p35 to p25 by calpain
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NATURE (2000)
Phosphorylation sites on tau identified by nanoelectrospray mass spectrometry:: Differences in vitro between the mitogen-activated protein kinases ERK2, c-Jun N-terminal kinase and P38, and glycogen synthase kinase-3β
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JOURNAL OF NEUROCHEMISTRY (2000)
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