期刊
MINI-REVIEWS IN MEDICINAL CHEMISTRY
卷 15, 期 5, 页码 406-426出版社
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/138955751505150408142958
关键词
Agents; antimicrobial; antitumoral; synthesis; organotin(IV)
资金
- Comision de Operacion y Fomento de Actividades Academicas (COFAA-Instituto Politecnico Nacional)
- programa de estimulos al desempeno de los investigadores (EDI-Instituto Politecnico Nacional)
Advances in the use of organotin(IV) compounds have gained relevant interest in both the chemical and pharmaceutical industry. Tin(IV) form stable complexes with a unique structure and physicochemical properties that are used in organic synthesis as heat stabilizers and catalysts, in drug development as biologically active agents, and in other areas. This review focuses on recent progress in the classical and convenient synthesis procedure, on their mechanism of action, and biological activities as antitumoral and antimicrobial agents.
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