相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Psychopharmacological Neuroprotection in Neurodegenerative Disease: Heuristic Clinical Applications
Edward C. Lauterbach et al.
JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES (2014)
Psychopharmacological Neuroprotection in Neurodegenerative Disease: Assessing the Preclinical Data
Edward C. Lauterbach et al.
JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES (2014)
Psychopharmacological Neuroprotection in Neurodegenerative Diseases, Part III: Criteria-Based Assessment: A Report of the ANPA Committee on Research
Edward C. Lauterbach et al.
JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES (2014)
miR-196a Ameliorates Phenotypes of Huntington Disease in Cell, Transgenic Mouse, and Induced Pluripotent Stem Cell Models
Pei-Hsun Cheng et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2013)
MicroRNA-124 targets CCNA2 and regulates cell cycle in STHdhQ111/HdhQ111 cells
Eashita Das et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2013)
Histone deacetylase class II and acetylated core histone immunohistochemistry in human brains with Huntington's disease
Hsin Hsien Yeh et al.
BRAIN RESEARCH (2013)
Mitochondrial Diseases of the Brain
Rajnish K. Chaturvedi et al.
FREE RADICAL BIOLOGY AND MEDICINE (2013)
Regulation of Huntingtin Gene Expression by miRNA-137,-214,-148a, and Their Respective isomiRs
Emilia Kozlowska et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2013)
Neuroprotective effects of the mood stabilizer lamotrigine against glutamate excitotoxicity: roles of chromatin remodelling and Bcl-2 induction
Yan Leng et al.
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2013)
Therapeutic Effects of Valproate Combined With Lithium Carbonate on MPTP-Induced Parkinsonism in Mice: Possible Mediation Through Enhanced Autophagy
Xue-zhong Li et al.
INTERNATIONAL JOURNAL OF NEUROSCIENCE (2013)
Dysregulation of REST-regulated coding and non-coding RNAs in a cellular model of Huntington's disease
Chiara Soldati et al.
JOURNAL OF NEUROCHEMISTRY (2013)
Neuroprotective effects of PPAR-γ agonist rosiglitazone in N171-82Q mouse model of Huntington's disease
Jing Jin et al.
JOURNAL OF NEUROCHEMISTRY (2013)
Genomic Landscape of Transcriptional and Epigenetic Dysregulation in Early Onset Polyglutamine Disease
Luis M. Valor et al.
JOURNAL OF NEUROSCIENCE (2013)
Antidepressants and mood stabilizers effects on histone deacetylase expression in C57BL/6 mice: Brain region specific changes
Masanori Ookubo et al.
JOURNAL OF PSYCHIATRIC RESEARCH (2013)
eRNAs Are Required for p53-Dependent Enhancer Activity and Gene Transcription
Carlos A. Melo et al.
MOLECULAR CELL (2013)
Increased 5-Methylcytosine and Decreased 5-Hydroxymethylcytosine Levels are Associated with Reduced Striatal A2AR Levels in Huntington's Disease
Izaskun Villar-Menendez et al.
NEUROMOLECULAR MEDICINE (2013)
Structural MRI in Huntington's disease and recommendations for its potential use in clinical trials
Nellie Georgiou-Karistianis et al.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2013)
MicroRNA-22 (miR-22) Overexpression Is Neuroprotective via General Anti-Apoptotic Effects and May also Target Specific Huntington's Disease-Related Mechanisms
Ana Jovicic et al.
PLOS ONE (2013)
Extensive changes in DNA methylation are associated with expression of mutant huntingtin
Christopher W. Ng et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Psychotropics regulate Skp1a, Aldh1a1, and Hspa8 transcription - Potential to delay Parkinson's disease
Edward C. Lauterbach
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2013)
Modulation of neuronal plasticity following chronic concomitant administration of the novel antipsychotic lurasidone with the mood stabilizer valproic acid
F. Calabrese et al.
PSYCHOPHARMACOLOGY (2013)
Off label use of lithium in the treatment of Huntington's disease: A case series
Vijay Danivas et al.
INDIAN JOURNAL OF PSYCHIATRY (2013)
Psychotropic Drug Effects on Gene Transcriptomics Relevant to Alzheimer Disease
Edward C. Lauterbach
ALZHEIMER DISEASE & ASSOCIATED DISORDERS (2012)
Huntington's Disease and its therapeutic target genes: a global functional profile based on the HD Research Crossroads database
Ravi Kiran Reddy Kalathur et al.
BMC NEUROLOGY (2012)
ATRX induction by mutant huntingtin via Cdx2 modulates heterochromatin condensation and pathology in Huntington's disease
J. Lee et al.
CELL DEATH AND DIFFERENTIATION (2012)
trans-(-)-ε-Viniferin Increases Mitochondrial Sirtuin 3 (SIRT3), Activates AMP-activated Protein Kinase (AMPK), and Protects Cells in Models of Huntington Disease
Jinrong Fu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Interrogation of brain miRNA and mRNA expression profiles reveals a molecular regulatory network that is perturbed by mutant huntingtin
Jing Jin et al.
JOURNAL OF NEUROCHEMISTRY (2012)
Histone deacetylase 1 is required for Carbamazepine-induced CYP3A4 expression
Yin Wu et al.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2012)
REST Is a Novel Prognostic Factor and Therapeutic Target for Medulloblastoma
Pete Taylor et al.
MOLECULAR CANCER THERAPEUTICS (2012)
Potential endpoints for clinical trials in premanifest and early Huntington's disease in the TRACK-HD study: analysis of 24 month observational data
Sarah J. Tabrizi et al.
LANCET NEUROLOGY (2012)
Selective G2/M arrest in a p53Val135-transformed cell line induced by lithium is mediated through an intricate network of MAPK and β-catenin signaling pathways
Marco Man Kin Tsui et al.
LIFE SCIENCES (2012)
Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targets
Mali Jiang et al.
NATURE MEDICINE (2012)
Sirt1 mediates neuroprotection from mutant huntingtin by activation of the TORC1 and CREB transcriptional pathway
Hyunkyung Jeong et al.
NATURE MEDICINE (2012)
NP03, a novel low-dose lithium formulation, is neuroprotective in the YAC128 mouse model of Huntington disease
Mahmoud A. Pouladi et al.
NEUROBIOLOGY OF DISEASE (2012)
Spatiotemporal mapping of brain atrophy in mouse models of Huntington's disease using longitudinal in vivo magnetic resonance imaging
Manisha Aggarwal et al.
NEUROIMAGE (2012)
Mechanism(s) of Alteration of Micro RNA Expressions in Huntington's Disease and Their Possible Contributions to the Observed Cellular and Molecular Dysfunctions in the Disease
Mithun Sinha et al.
NEUROMOLECULAR MEDICINE (2012)
Psychotropic drug effects on gene transcriptomics relevant to Parkinson's disease
Edward C. Lauterbach
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2012)
PGC-1α Rescues Huntington's Disease Proteotoxicity by Preventing Oxidative Stress and Promoting TFEB Function
Taiji Tsunemi et al.
SCIENCE TRANSLATIONAL MEDICINE (2012)
The Sirtuin 2 Inhibitor AK-7 Is Neuroprotective in Huntington's Disease Mouse Models
Vanita Chopra et al.
CELL REPORTS (2012)
Altered microRNA regulation in Huntington's disease models
Soon-Tae Lee et al.
EXPERIMENTAL NEUROLOGY (2011)
Mitogen- and stress-activated protein kinase 1-induced neuroprotection in Huntington's disease: role on chromatin remodeling at the PGC-1-alpha promoter
Elodie Martin et al.
HUMAN MOLECULAR GENETICS (2011)
Hsa-miR-34b is a plasma-stable microRNA that is elevated in pre-manifest Huntington's disease
Philip Michael Gaughwin et al.
HUMAN MOLECULAR GENETICS (2011)
Early atrophy of pallidum and accumbens nucleus in Huntington's disease
Simon J. A. van den Bogaard et al.
JOURNAL OF NEUROLOGY (2011)
Longitudinal change in regional brain volumes in prodromal Huntington disease
Elizabeth H. Aylward et al.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2011)
The Melatonin MT1 Receptor Axis Modulates Mutant Huntingtin-Mediated Toxicity
Xin Wang et al.
JOURNAL OF NEUROSCIENCE (2011)
Chronic Suppression of Phosphodiesterase 10A Alters Striatal Expression of Genes Responsible for Neurotransmitter Synthesis, Neurotransmission, and Signaling Pathways Implicated in Huntington's Disease
Robin J. Kleiman et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2011)
Novel protective mechanisms of antidepressants against 3-nitropropionic acid induced Huntington's-like symptoms: a comparative study
Puneet Kumar et al.
JOURNAL OF PSYCHOPHARMACOLOGY (2011)
Development of biomarkers for Huntington's disease
David W. Weir et al.
LANCET NEUROLOGY (2011)
Biological and clinical changes in premanifest and early stage Huntington's disease in the TRACK-HD study: the 12-month longitudinal analysis
Sarah J. Tabrizi et al.
LANCET NEUROLOGY (2011)
The Tricyclic Antidepressant Amitriptyline Inhibits D-Cyclin Transactivation and Induces Myeloma Cell Apoptosis by Inhibiting Histone Deacetylases: In Vitro and In Silico Evidence
Xinliang Mao et al.
MOLECULAR PHARMACOLOGY (2011)
Basal ganglia atrophy in prodromal Huntington's disease is detectable over one year using automated segmentation
D. S. Adnan Majid et al.
MOVEMENT DISORDERS (2011)
Structural MRI detects progressive regional brain atrophy and neuroprotective effects in N171-82Q Huntington's disease mouse model
Yong Cheng et al.
NEUROIMAGE (2011)
An Antisense CAG Repeat Transcript at JPH3 Locus Mediates Expanded Polyglutamine Protein Toxicity in Huntington's Disease-like 2 Mice
Brian Wilburn et al.
NEURON (2011)
Combined Treatment with the Mood Stabilizers Lithium and Valproate Produces Multiple Beneficial Effects in Transgenic Mouse Models of Huntington's Disease
Chi-Tso Chiu et al.
NEUROPSYCHOPHARMACOLOGY (2011)
POTENTIAL AUTOPHAGY ENHANCERS ATTENUATE ROTENONE-INDUCED TOXICITY IN SH-SY5Y
N. Xiong et al.
NEUROSCIENCE (2011)
Hippocampal-dependent antidepressant-like activity of histone deacetylase inhibition
Herbert E. Covington et al.
NEUROSCIENCE LETTERS (2011)
Regulation of miR-146a by RelA/NFkB and p53 in STHdhQ111/HdhQ111 Cells, a Cell Model of Huntington's Disease
Jayeeta Ghose et al.
PLOS ONE (2011)
Brain-Derived Neurotrophic Factor in Patients with Huntington's Disease
Chiara Zuccato et al.
PLOS ONE (2011)
SAHA Decreases HDAC 2 and 4 Levels In Vivo and Improves Molecular Phenotypes in the R6/2 Mouse Model of Huntington's Disease
Michal Mielcarek et al.
PLOS ONE (2011)
Transcriptional modulator H2A histone family, member Y (H2AFY) marks Huntington disease activity in man and mouse
Yi Hu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Micro RNA-214,-150,-146a and-125b target Huntingtin gene
Mithun Sinha et al.
RNA BIOLOGY (2011)
Neurodegenerative processes in Huntington's disease
D. Bano et al.
CELL DEATH & DISEASE (2011)
Nitric oxide mechanism in the protective effect of antidepressants against 3-nitropropionic acid-induced cognitive deficit, glutathione and mitochondrial alterations in animal model of Huntington's disease
Puneet Kumar et al.
BEHAVIOURAL PHARMACOLOGY (2010)
Altered microRNAs in STHdhQ111/HdhQ111 cells: miR-146a targets TBP
Mithun Sinha et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)
Inhibition of transglutaminase 2 mitigates transcriptional dysregulation in models of Huntington's disease
Stephen J. McConoughey et al.
EMBO MOLECULAR MEDICINE (2010)
Inhibiting p53 pathways in microglia attenuates microglial-evoked neurotoxicity following exposure to Alzheimer peptides
Christopher M. Davenport et al.
JOURNAL OF NEUROCHEMISTRY (2010)
The progression of regional atrophy in premanifest and early Huntington's disease: a longitudinal voxel-based morphometry study
Nicola Z. Hobbs et al.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2010)
Tetrabenazine is neuroprotective in Huntington's disease mice
Hongyu Wang et al.
MOLECULAR NEURODEGENERATION (2010)
A Futility Study of Minocycline in Huntington's Disease
Heidi Schwarz et al.
MOVEMENT DISORDERS (2010)
The role of REST in transcriptional and epigenetic dysregulation in Huntington's disease
Noel J. Buckley et al.
NEUROBIOLOGY OF DISEASE (2010)
A myriad of miRNA variants in control and Huntington's disease brain regions detected by massively parallel sequencing
Eulalia Marti et al.
NUCLEIC ACIDS RESEARCH (2010)
Slowed Progression in Models of Huntington Disease by Adipose Stem Cell Transplantation
Soon-Tae Lee et al.
ANNALS OF NEUROLOGY (2009)
Transcriptional dysregulation of coding and non-coding genes in cellular models of Huntington's disease
Angela Bithell et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2009)
Evidence for an effect of clozapine on the regulation of fat-cell derived factors
Zhi Yang et al.
CLINICA CHIMICA ACTA (2009)
Mouse models of Huntington disease: variations on a theme
Dagmar E. Ehrnhoefer et al.
DISEASE MODELS & MECHANISMS (2009)
Relationship between CAG repeat length and brain volume in premanifest and early Huntington's disease
Susie M. D. Henley et al.
JOURNAL OF NEUROLOGY (2009)
Epigenetic mechanisms in neurological diseases: genes, syndromes, and therapies
Rocio G. Urdinguio et al.
LANCET NEUROLOGY (2009)
Evidence of calpain/cdk5 pathway inhibition by lithium in 3-nitropropionic acid toxicity in vivo and in vitro
N. Crespo-Biel et al.
NEUROPHARMACOLOGY (2009)
Valproate ameliorates the survival and the motor performance in a transgenic mouse model of Huntington's disease
Denes Zadori et al.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2009)
Possible role of sertraline against 3-nitropropionic acid induced behavioral, oxidative stress and mitochondrial dysfunctions in rat brain
Puneet Kumar et al.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2009)
Huntington's disease: the case for genetic modifiers
James F. Gusella et al.
GENOME MEDICINE (2009)
Therapeutic interventions for disease progression in Huntington's disease
Tiago Mestre et al.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2009)
The mood stabilizers lithium and valproate selectively activate the promoter IV of brain-derived neurotrophic factor in neurons
S. Yasuda et al.
MOLECULAR PSYCHIATRY (2009)
Chromosomal profiles of gene expression in Huntington's disease
Alexander N. Anderson et al.
BRAIN (2008)
Mutant p53 protein localized in the cytoplasm inhibits autophagy
Eugenia Morselli et al.
CELL CYCLE (2008)
Lithium-induced suppression of transcription repressor NRSF/REST: Effects on the dysfunction of neuronal differentiation by ethanol
Takao Ishii et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2008)
The antidepressant sertraline improves the phenotype, promotes neurogenesis and increases BDNF levels in the R6/2 Huntington's disease mouse model
Qi Peng et al.
EXPERIMENTAL NEUROLOGY (2008)
Mitogen- and stress-activated protein kinase-1 deficiency is involved in expanded-huntingtin-induced transcriptional dysregulation and striatal death
Emmanuel Roze et al.
FASEB JOURNAL (2008)
Dopamine determines the vulnerability of striatal neurons to the N-terminal fragment of mutant huntingtin through the regulation of mitochondrial complex II
Alexandra Benchoua et al.
HUMAN MOLECULAR GENETICS (2008)
Valproic acid increases expression of methylenetetrahydrofolate reductase (MTHFR) and induces lower teratogenicity in MTHFR deficiency
Marc Roy et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2008)
Long-lasting depression-like behavior and epigenetic changes of BDNF gene expression induced by perinatal exposure to methylmercury
Natalia Onishchenko et al.
JOURNAL OF NEUROCHEMISTRY (2008)
Longitudinal analysis of regional grey matter loss in Huntington disease: effects of the length of the expanded CAG repeat
H. H. Ruocco et al.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2008)
Detection of Huntington's disease decades before diagnosis: the Predict-HD study
J. S. Paulsen et al.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2008)
Altered histone monoubiquitylation mediated by mutant Huntingtin induces transcriptional dysregulation
Mee-Ohk Kim et al.
JOURNAL OF NEUROSCIENCE (2008)
The Bifunctional microRNA miR-9/miR-9*Regulates REST and CoREST and Is Downregulated in Huntington's Disease
Amy N. Packer et al.
JOURNAL OF NEUROSCIENCE (2008)
Regulation of autophagy by cytoplasmic p53
Ezgi Tasdemir et al.
NATURE CELL BIOLOGY (2008)
A microRNA-based gene dysregulation pathway in Huntington's disease
Rory Johnson et al.
NEUROBIOLOGY OF DISEASE (2008)
Haloperidol protects striatal neurons from dysfunction induced by mutated huntingtin in vivo
Delphine Charvin et al.
NEUROBIOLOGY OF DISEASE (2008)
Sertraline slows disease progression and increases neurogenesis in N171-82Q mouse model of Huntington's disease
Wenzhen Duan et al.
NEUROBIOLOGY OF DISEASE (2008)
Modulation of SIRT1 expression in different neurodegenerative models and human pathologies
M. Pallas et al.
NEUROSCIENCE (2008)
The HDAC inhibitor 4b ameliorates the disease phenotype and transcriptional abnormalities in Huntington's disease transgenic mice
Elizabeth A. Thomas et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Genetic regulation of behavioral and neuronal responses to fluoxetine
Brooke H. Miller et al.
NEUROPSYCHOPHARMACOLOGY (2008)
Endoplasmic reticulum stress increases the expression of methylenetetrahydrofolate reductase through the IRE1 transducer
Daniel Leclerc et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Dynamic histone H3 methylation during gene induction: HYPB/Setd2 mediates all H3K36 trimethylation
John W. Edmunds et al.
EMBO JOURNAL (2008)
A rational mechanism for combination treatment of Huntington's disease using lithium and rapamycin
Sovan Sarkar et al.
HUMAN MOLECULAR GENETICS (2008)
Restraint stress influences AP-1 and CREB DNA-binding activity induced by chronic lithium treatment in the rat frontal cortex and hippocampus
Jeannette C. Miller et al.
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2007)
Histone deacetylase inhibitors reduce steroidogenesis through SCF-mediated ubiquitination and degradation of steroidogenic factor 1 (NR5A1)
Wei-Yi Chen et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
Riluzole in Huntington's disease: A 3-year, randomized controlled study
G. Bernhard Landwehrmeyer et al.
ANNALS OF NEUROLOGY (2007)
Defective cholesterol traffic and neuronal differentiation in neural stem cells of Niemann-Pick type C disease improved by valproic acid, a histone deacetylase inhibitor
Sun-Jung Kim et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
Nortriptyline delays disease onset in models of chronic neurodegeneration
Hongyan Wang et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2007)
Dopaminergic signaling and striatal neurodegeneration in Huntington's disease
Tie-Shan Tang et al.
JOURNAL OF NEUROSCIENCE (2007)
Histones associated with downregulated genes are hypo-acetylated in Huntington's disease models
Ghazaleh Sadri-Vakili et al.
HUMAN MOLECULAR GENETICS (2007)
Targeting AML1/ETO-histone deacetylase repressor complex: A novel mechanism for valproic acid-mediated gene expression and cellular differentiation in AML1/ETO-positive acute myeloid leukemia cells
Shujun Liu et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2007)
OGG1 initiates age-dependent CAG trinucleotide expansion in somatic cells
Irina V. Kovtun et al.
NATURE (2007)
Sodium valproate exerts neuroprotective effects in vivo through CREB-binding protein-dependent mechanisms but does not improve survival in an amyotrophic lateral sclerosis mouse model
Caroline Rouaux et al.
JOURNAL OF NEUROSCIENCE (2007)
Modulation of nucleosome dynamics in Huntington's disease
Edward C. Stack et al.
HUMAN MOLECULAR GENETICS (2007)
Effect of chronic citalopram on serotonin-related and stress-regulated genes in the dorsal raphe nucleus of the rat
Nashat Abumaria et al.
EUROPEAN NEUROPSYCHOPHARMACOLOGY (2007)
Histone deacetylase 6 inhibition compensates for the transport deficit in Huntington's disease by increasing tubulin acetylation
Jim P. Dompierre et al.
JOURNAL OF NEUROSCIENCE (2007)
Replication of twelve association studies for Huntington's disease residual age of onset in large Venezuelan kindreds
J. M. Andresen et al.
JOURNAL OF MEDICAL GENETICS (2007)
ESET/SETDB1 gene expression and histone H3 (K9) trimethylation in Huntington's disease
Hoon Ryu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
MicroRNA pathways modulate polyglutamine-induced neurodegeneration
Julide Bilen et al.
MOLECULAR CELL (2006)
Transcriptional repression of PGC-α by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration
Libin Cui et al.
CELL (2006)
Chronic olanzapine treatment causes differential expression of genes in frontal cortex of rats as revealed by DNA microarray technique
S. Hossein Fatemi et al.
NEUROPSYCHOPHARMACOLOGY (2006)
Valproate inhibition of histone deacetylase 2 affects differentiation and decreases proliferation of endometrial stromal sarcoma cells
Andelko Hrzenjak et al.
MOLECULAR CANCER THERAPEUTICS (2006)
Depletion of CBP is directly caused by mutant huntingtin
Haibing Jiang et al.
NEUROBIOLOGY OF DISEASE (2006)
Fluoxetine and cocaine induce the epigenetic factors MeCP2 and MBD1 in adult rat brain
Suzanne Cassel et al.
MOLECULAR PHARMACOLOGY (2006)
Chemical modifiers of unstable expanded simple sequence repeats: What goes up, could come down
Mario Gomes-Pereira et al.
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2006)
Inositol and IP3 levels regulate autophagy - Biology and therapeutic speculations
Sovan Sarkar et al.
AUTOPHAGY (2006)
被撤回的出版物: Decrease in the AP-2 DNA-binding activity and in the protein expression of AP-2 α and AP-2 β in frontal cortex of rats treated with lithium for 6 weeks (Retracted article. See vol. 42, pg. 456, 2018)
JS Rao et al.
NEUROPSYCHOPHARMACOLOGY (2005)
Histone deacetylases in acute myeloid leukaemia show a distinctive pattern of expression that changes selectively in response to deacetylase inhibitors
C Bradbury et al.
LEUKEMIA (2005)
Cognitive disorders and neurogenesis deficits in Huntington's disease mice are rescued by fluoxetine
HE Grote et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2005)
Lithium induces autophagy by inhibiting inositol monophosphatase
S Sarkar et al.
JOURNAL OF CELL BIOLOGY (2005)
Unraveling a role for dopamine in Huntington's disease:: The dual role of reactive oxygen species and D2 receptor stimulation
D Charvin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Ethyl-EPA in Huntington disease - A double-blind, randomized, placebo-controlled trial
BK Puri et al.
NEUROLOGY (2005)
Disturbed Ca2+ signaling and apoptosis of medium spiny neurons in Huntington's disease
TS Tang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Neuroprotective effects of phenylbutyrate in the N171-82Q transgenic mouse model of Huntington's disease
G Gardian et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Short-term lithium treatment promotes neuronal survival and proliferation in rat striatum infused with quinolinic acid, an excitotoxic model of Huntington's disease
VV Senatorov et al.
MOLECULAR PSYCHIATRY (2004)
Regulatory role of glycogen synthase kinase 3 for transcriptional activity of ADD1/SREBP1c
KH Kim et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Onset and rate of striatal atrophy in preclinical Huntington disease
EH Aylward et al.
NEUROLOGY (2004)
Chemotherapy for the brain: The antitumor antibiotic mithramycin prolongs survival in a mouse model of Huntington's disease
RJ Ferrante et al.
JOURNAL OF NEUROSCIENCE (2004)
Creatine supplementation in Huntington's disease - A placebo-controlled pilot trial
P Verbessem et al.
NEUROLOGY (2003)
Histone deacetylase activity is retained in primary neurons expressing mutant huntingtin protein
M Hoshino et al.
JOURNAL OF NEUROCHEMISTRY (2003)
Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes
C Zuccato et al.
NATURE GENETICS (2003)
Chronic lithium chloride treatment has variable effects on motor behaviour and survival of mice transgenic for the Huntington's disease mutation
NI Wood et al.
BRAIN RESEARCH BULLETIN (2003)
Modulation of age at onset in Huntington's disease and spinocerebellar ataxia type 2 patients originated from eastern India
B Chattopadhyay et al.
NEUROSCIENCE LETTERS (2003)
Chronic treatment with a low dose of lithium protects the brain against ischemic injury by reducing apoptotic death
JH Xu et al.
STROKE (2003)
Histone H3 is aberrantly phosphorylated in glutamine-repeat diseases
I Yazawa et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's disease
E Hockly et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Regulation of c-Jun N-terminal kinase, p38 kinase and AP-1 DNA binding in cultured brain neurons: roles in glutamate excitotoxicity and lithium neuroprotection
RW Chen et al.
JOURNAL OF NEUROCHEMISTRY (2003)
Metabolism to dextrorphan is not essential for dextromethorphan's anticonvulsant activity against kainate in mice
HC Kim et al.
LIFE SCIENCES (2003)
Glycogen synthase kinase-3β inhibitors prevent cellular polyglutamine toxicity caused by the Huntington's disease mutation
J Carmichael et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
In utero ethanol suppresses cerebellar activator protein-1 and nuclear factor-κB transcriptional activation in a rat fetal alcohol syndrome model
GK Acquaah-Mensah et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2002)
Huntington's disease: a review of the literature on prevalence and treatment of neuropsychiatric phenomena
P Naarding et al.
EUROPEAN PSYCHIATRY (2001)
Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila
JS Steffan et al.
NATURE (2001)
Lithium inhibits cell cycle progression and induces stabilization of p53 in bovine aortic endothelial cells
CD Mao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Lithium regulates PKC-mediated intracellular cross-talk and gene expression in the CNS in vivo
G Chen et al.
BIPOLAR DISORDERS (2000)
The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription
JS Steffan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)