期刊
INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY
卷 304, 期 1, 页码 37-43出版社
ELSEVIER GMBH
DOI: 10.1016/j.ijmm.2013.08.009
关键词
Antibiotics; Cyclic lipopeptides; Mode of action; Polymyxin; Daptomycin
资金
- Deutsche Forschungsgemeinschaft (DFG) [GR 2673/2-2]
- SCHN [1284/1-2]
Cyclic lipopeptides (CLPs) are a promising class of natural products with antibiotic properties. CLPs are amphiphilic molecules, composed of a fatty acid tail linked to a short oligopeptide which form a macrocylic ring structure. This review presents an overview of this class of antibiotics, focusing on the current and potential therapeutic applications and placing particular emphasis on the molecular modes of action of these compounds. (c) 2013 Elsevier GmbH. All rights reserved.
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