Heck coupling in the gas phase: Examination of the reaction mechanism by ion/molecule reactions and mass spectrometry

The Heck reaction of isoprene with (p-iodophenyl)-trimethylammonium iodide was conducted in the gas phase. Relevant species of the catalytic cycle including the ionic product of the Pd-catalyzed coupling reaction were reliably characterized by exact ion mass measurements and by characteristic product ions generated by tandem-MS. (C) 2011 Elsevier B.V. All rights reserved.