期刊
INTERNATIONAL JOURNAL OF MASS SPECTROMETRY
卷 303, 期 2-3, 页码 129-136出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.ijms.2011.01.021
关键词
Nucleotide; Mononucleotide; Photodissociation; Fragmentation
资金
- National Science Foundation through the JILA Atomic, Molecular and Optical Physics Frontier Center [PHY-0551010, CHE-0845618]
Irradiation of nucleotides in the gas phase with ultraviolet light can lead to their fragmentation. We present a comparison of UV photofragmentation data on ribo-, deoxyribo- and cyclic nucleotides with guanine and adenine as nucleobases. The envelope of the UV photofragment spectra does not depend significantly on the detailed structure of the sugar-phosphate backbone. The fragment channels observed in the photofragmentation of ribonucleotides are very similar to those of deoxyribonucleotides with small differences in the relative abundances of the product ions. In fragmentation of cyclic nucleotides, the deprotonated base anions are the most abundant fragments, in contrast to the non-cyclic nucleotides, where this channel is significantly weaker. We discuss the abundances in the context of possible fragmentation mechanisms and structural differences of the parent molecules. (C) 2011 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据