A micro RNA-146a polymorphism is associated with coronary restenosis

The association of the miRNA-146a polymorphism rs2910164 with atherosclerosis and restenosis was investigated. We found no association with atherosclerosis; however, we found a negative association for the G/C (P=0.007) and a positive association for the C/C genotype with the risk of restenosis, which is the main drawback for cardiac surgery.