期刊
INTERNATIONAL JOURNAL OF HYPERTHERMIA
卷 29, 期 8, 页码 810-818出版社
INFORMA HEALTHCARE
DOI: 10.3109/02656736.2013.838646
关键词
Cell death; inductive heating; magnetic hyperthermia; magnetic nanoparticles; superparamagnetism
资金
- Spanish Ministerio de Economia y Competitividad (MINECO) [MAT2010-19326]
- HelloKit INNPACTO
This review analyses the advances in the field of magnetically induced cell death using intracellular magnetic nanoparticles (MNPs). Emphasis has been given to in vitro research results, discussing the action of radiofrequency (RF) waves on biological systems as well as those results of thermally induced cell death in terms of MNP cell interactions. Our main goal has been to provide a unified depiction of many recent experiments and theoretical models relevant to the effect of applied electromagnetic fields on MNPs after cellular uptake and the cytotoxicity assessment of MNPs. We have addressed the effects of RF waves used for in vitro magnetic hyperthermia on eukaryotic cells regarding physical modifications of the cellular local environment and cell viability.
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