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BLOOD (2008)
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Oncogenic K-ras cooperates with PML-RARα to induce an acute promyelocytic leukemia-like disease
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Incidence and prognostic impact of c-Kit, FLT3, and Ras gene mutations in core binding factor acute myeloid leukemia (CBF-AML)
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Hyperactivation of the RAS signaling pathway in myelodysplastic syndrome with AML1/RUNX1 point mutations
H Niimi et al.
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KIT mutations, and not FLT3 internal tandem duplication, are strongly associated with a poor prognosis in pediatric acute myeloid leukemia with t(8;21):: a study of the Japanese Childhood AML Cooperative Study Group
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BLOOD (2006)
K-Ras mutations and N-Ras mutations in childhood acute leukemias with or without mixed-lineage leukemia gene rearrangements
DC Liang et al.
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Relationship between FLT3 mutation status, biologic characteristics, and response to targeted therapy in acute promyelocytic leukemia
RE Gale et al.
BLOOD (2005)
Mutations of genes in the receptor tyrosine kinase (RTK)/RAS-BRAF signal transduction pathway in therapy-related myelodysplasia and acute myeloid leukemia
DH Christiansen et al.
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Haploinsufficiency of Runx1/AML1 promotes myeloid features and leukaemogenesis in BXH2 mice
N Yamashita et al.
BRITISH JOURNAL OF HAEMATOLOGY (2005)
Direct evidence for cooperating genetic events in the leukemic transformation of normal human hematopoietic cells
JK Warner et al.
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The AML1-ETO fusion gene and the FLT3 length mutation collaborate in inducing acute leukemia in mice
C Schessl et al.
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Prognostic implication of FLT3 and Ras gene mutations in patients with acute promyelocytic leukemia (APL):: a retrospective study from the European APL Group
C Callens et al.
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Dimerization of MLL fusion proteins and FLT3 activation synergize to induce multiple-lineage leukemogenesis
R Ono et al.
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AML1-ETO and C-KIT mutation/overexpression in t(8;21) leukemia:: Implication in stepwise leukemogenesis and response to Gleevec
YY Wang et al.
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High incidence of somatic mutations in the AML1/RUNX1 gene in myelodysplastic syndrome and low blast percentage myeloid leukemia with myelodysplasia
H Harada et al.
BLOOD (2004)
FLT3 mutations in the activation loop of tyrosine kinase domain are frequently found in infant ALL with MLL rearrangements and pediatric ALL with hyperdiploidy
T Taketani et al.
BLOOD (2004)
A novel gene, FGA7, is fused to RUNXI/AMLI in a t(4;21)(q28;q22) in a patient with T-cell acute lymphoblastic leukemia
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Incidence and prognosis of c-KIT and FLT3 mutations in core binding factor (CBF) acute myeloid leukaemias
RS Care et al.
BRITISH JOURNAL OF HAEMATOLOGY (2003)
M0 AML, clinical and biologic features of the disease, including AML1 gene mutations:: a report of 59 cases by the Groupe Francais d'Hematologie Cellulaire (GFHC) and the Groupe Francais de Cytogenetique Hematologique (GFCH)
C Roumier et al.
BLOOD (2003)
FLT3 internal tandem duplication in childhood acute myeloid leukaemia: association with hyperleucocytosis in acute promyelocytic leukaemia
P Arrigoni et al.
BRITISH JOURNAL OF HAEMATOLOGY (2003)
Dual mutations in the AML1 and FLT3 genes are associated with leukemogenesis in acute myeloblastic leukemia of the M0 subtype
N Matsuno et al.
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Alterations of the FLT3 gene in acute promyelocytic leukemia: association with diagnostic characteristics and analysis of clinical outcome in patients treated with the Italian AIDA protocol
N Noguera et al.
LEUKEMIA (2002)
RasGRP4 is a novel Ras activator isolated from acute myeloid leukemia
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JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
RasGRP4, a new mast cell-restricted Ras guanine nucleotide-releasing protein with calcium- and diacylglycerol-binding motifs - Identification of defective variants of this signaling protein in asthma, mastocytosis, and mast cell leukemia patients and demonstration of the importance of RasGRP4 in mast cell development and function
Y Yang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
PML/RARα and FLT3-ITD induce an APL-like disease in a mouse model
LM Kelly et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Cooperation of BCR-ABL and AML1/MDS1/EVI1 in blocking myeloid differentiation and rapid induction of an acute myelogenous leukemia
GM Cuenco et al.
ONCOGENE (2001)
FLT3, RAS, and TP53 mutations in elderly patients with acute myeloid leukemia
DL Stirewalt et al.
BLOOD (2001)