期刊
INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY
卷 149, 期 3, 页码 274-277出版社
ELSEVIER
DOI: 10.1016/j.ijfoodmicro.2011.07.006
关键词
Salmonella; Antimicrobial resistance; Class 1 integron; Gene transfer
资金
- National Natural Science Foundation of China [20877028]
- Major State Basic Research Development Program of China (973 Program) [2010CB735700]
- China Postdoctoral Science Foundation [200902327]
- Guangdong Nature Science Foundation of China [10451064101005159]
- SCUT [2009ZM0224]
A total of 81 Salmonella isolates from retail meats and seafood in Hebei province, China, were assayed for the presence of and horizontal transfer of class 1 integrons. By the PCR screening for the integrons, class 1 integron was detected from strains in serotypes of Derby, Indiana, London and Choleraesuis, which were isolated from pork, chicken or seafood: however, two isolates contained the empty integron that lacked the resistance cassette, a potential hotspot for development of the multidrug resistance. In contrast, two other isolates had the antibiotic resistance gene cassettes within the class 1 integron, which were dfrA1-aadA1 and aadB-cmlA, respectively. The conjugation experiments demonstrated the plasmid-mediated transfer of the class 1 integrons. Furthermore, each of the integrons was transmitted to Streptococcus mutans via natural gene transformation. These findings suggest the possible transfer of class 1 integrons from foodborne pathogens to human residential bacteria via horizontal gene transfer. (C) 2011 Elsevier B.V. All rights reserved.
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