期刊
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
卷 43, 期 4, 页码 1063-1072出版社
OXFORD UNIV PRESS
DOI: 10.1093/ije/dyt086
关键词
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资金
- Medical Research Council, UK [G0401527]
- Cancer Research UK [C864/A8257]
- Research into Ageing [262]
- Wellcome Trust
- Medical Research Council [MC_UU_12015/1, G1000143, G0401527, MC_U106179471] Funding Source: researchfish
- National Institute for Health Research [NF-SI-0611-10084, NF-SI-0512-10114] Funding Source: researchfish
- MRC [MC_UU_12015/1] Funding Source: UKRI
The European Prospective Investigation of Cancer (EPIC) is a 10-country collaborative study in which EPIC-Norfolk is one of the UK centres. EPIC-Norfolk examined 25 639 men and women resident in East Anglia (aged 40-79 years), between 1993 and 1997. The EPIC collaboration was set up to examine the dietary determinants of cancer, but the remit in the EPIC-Norfolk cohort was broadened from the outset to include determinants of other health conditions and chronic diseases. EPIC-Norfolk completed a third round of health examinations (EPIC-Norfolk 3 or 3HC) in December 2011, on 8623 participants in the age range 48-92 years. EPIC-Norfolk focused on objective measures of cognitive function, physical capability and visual health, adapting this existing mid-life cohort to the current need to investigate healthy and independent living for ageing societies. With a wealth of longitudinal data and a biobank (including DNA) collected at up to three separate time points, EPIC-Norfolk offers the unique opportunity to investigate the association of lifestyle and biological factors, including genetic exposures, with a range of health outcomes in middle and later life. Information for data access can be found on the study website, details as given in this cohort profile.
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