期刊
INTERNATIONAL JOURNAL OF DATA MINING AND BIOINFORMATICS
卷 5, 期 5, 页码 532-557出版社
INDERSCIENCE ENTERPRISES LTD
DOI: 10.1504/IJDMB.2011.043034
关键词
computational neuroscience and psychiatry; dimensional approach; unified bipolar disorder classification; exploratory neurobiological data mining; YinYang bipolar support vector machines
MentalSquares (MSQs) - an equilibrium- based dimensional approach is presented for the classification and diagnostic analysis of psychological conditions with Bipolar Disorders (BPDs) as an example. While a Support Vector Machine (SVM) is defined in Hilbert space. A MSQ can be considered as a generic SVM for improved classification. Different from the traditional categorical model of BPDs, the generic approach focuses on the balance of two poles of mental equilibrium. Preliminary results show that this new approach has a number of advantages over existing models. The generic model is analytically illustrated with public domain clinical examples and well-known empirical clinical knowledge. Its clinical and computerised operability is illustrated. Its potential of being a practical method for the classification and analysis of neurobiological patterns and drug effects is discussed.
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