Polymer-immobilized α,α-bis[bis-3,5-(trifluoromethyl)phenyl]prolinol silyl ether: synthesis and application in the asymmetric α-amination of aldehydes

alpha,alpha-Bis[bis-3,5-(trifluoromethyl)phenyl]prolinol silyl ether anchored onto polystyrene was synthesized and tested in asymmetric alpha-amination of aldehydes. The catalytic activity and enantioselectivity of the immobilized catalyst persist for 3 cycles.