期刊
MEMORIAS DO INSTITUTO OSWALDO CRUZ
卷 110, 期 4, 页码 569-572出版社
FUNDACO OSWALDO CRUZ
DOI: 10.1590/0074-02760150192
关键词
Zika virus; dengue-like syndrome; Brazil
In the early 2015, several cases of patients presenting symptoms of mild fever, rash, conjunctivitis and arthralgia were reported in the northeastern Brazil. Although all patients lived in a dengue endemic area, molecular and serological diagnosis for dengue resulted negative. Chikungunya virus infection was also discarded. Subsequently, Zika virus (ZIKV) was detected by reverse transcription-polymerase chain reaction from the sera of eight patients and the result was confirmed by DNA sequencing. Phylogenetic analysis suggests that the ZIKV identified belongs to the Asian clade. This is the first report of ZIKV infection in Brazil.
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