期刊
INTERNATIONAL JOURNAL OF CARDIOLOGY
卷 269, 期 -, 页码 298-303出版社
ELSEVIER IRELAND LTD
DOI: 10.1016/j.ijcard.2018.07.111
关键词
Intramural hematoma; Aorta; Intimal disruption; Multidetector computed tomography; Endovascular treatment
Background: Type B intramural hematoma (IMH) is considered a low-risk entity for aortic complications if aortic dilation, containing rupture or clinical instability are absent. However, the development of intimal disruptions (ID), present in >40% of cases, poses an unknown risk. Objectives: To establish which ID characteristics imply a higher risk of aortic complications and, therefore, merit invasive treatment. Methods: A systematic review and a meta-analysis were made following a search in EMBASE, MEDLINE and PsycINFO for articles published between January 1995 and December 2017. The combined endpoint was defined as aortic mortality, invasive treatment for aortic disease and/or increase in maximum aortic diameter >= 55 mm. Lesionswith communicating orifice <= 3 mm were defined as tiny ID (TID) and those with >3 mm as focal ID (FID). Results: Six studies with 564 participants diagnosed of type B IMH were included. Incidence of ID was 54.3% (306 individuals): 27.7% (156 individuals) initially met TID criteria; however, 13.9% of these (21 of 151 with morphologic evolution) evolved to FID within the first 6 months. Ninety-two cases suffered clinical aorta-related events (16.3%; mean follow-up range: 15-85 months; median: 52 months). Patients with TID had a similar risk of aorta-related events to those without ID (RR = 0.904; 95% CI, 0.335-2.440; P = 0.842; I-2 = 42.5%), but lower than those with FID (RR = 0.299; 95% CI, 0.094-0.952; P = 0.041; I-2 = 26.9%). Conclusions: Tiny intimal disruption in type B IMH evolution is not related to an increased risk of complications and should not be considered an indication for invasive treatment. However, since 14% of TID evolve to FID within the first 6 months, close follow-up with imaging techniques is advisable. (c) 2018 Elsevier B.V. All rights reserved.
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