期刊
INTERNATIONAL JOURNAL OF CARDIOLOGY
卷 129, 期 2, 页码 163-171出版社
ELSEVIER IRELAND LTD
DOI: 10.1016/j.ijcard.2008.02.004
关键词
pulmonary arterial hypertension; adult congenital heart disease; operability; advanced therapies
资金
- European Society of Cardiology
- Spanish Society of Cardiology
- Clinical Research Committee
- Royal Brompton Hospital, London, UK
- British Heart Foundation
Pulmonary arterial hypertension (PAH) associated with congenital heart disease remains a major problem despite advances in cardiac surgery. Recently, advanced therapies for PAH have become available and have been effective in reducing pulmonary vascular resistance and symptoms in patients with near-systemic pulmonary arterial pressures, previously thought to have irreversible pulmonary vascular disease. This has led to a new dilemma, namely could intracardiac communications previously considered inoperable due to severe pulmonary vascular disease become amenable to surgery after successful treatment with advanced therapy? We address, hereby, the potential merits and hazards of a treat-and-repair approach using advanced therapies in patients with PAH associated with congenital heart disease. (C) 2008 Elsevier Ireland Ltd. All rights reserved.
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