期刊
INTERNATIONAL JOURNAL OF CANCER
卷 124, 期 4, 页码 964-969出版社
WILEY
DOI: 10.1002/ijc.23969
关键词
cervical cancer; HPV; SUCCEED; epidemiology; molecular; CIN; biomarker
类别
资金
- Intramural NIH HHS [Z01 CP010124-12] Funding Source: Medline
Diagnosis and treatment of cervical cancer precursors rely on colposcopic biopsy, which is sometimes [tampered by incorrect biopsy placement an the unclear prognostic value of poorly reproducible diagnoses such as cervical intraepithelial neoplasia WIN) Grade 1 and 2. Searching for discrete disease categories that incorporate the value or cytology and that reflect the causal role of particular HPV types, we analyzed histology, cytology and HPV genotype distributions in the Study to Understand Cervical Cancer Endpoints and Early Determinants (SUCCEED). This cross-sectional study comprises similar to 1,700 women referred to colposcopy or treatment for the spectrum of cervical disease, including 439 women with
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