In vitro effects of a novel polysaccharide from the seeds of Plantago asiatica L. on intestinal function

Effects of a novel polysaccharide (PLP) from the seeds of Mantago asiatica L on intestinal function were investigated in vitro. Results showed that PLP had notable influence on slowing down glucose diffusion and inhibiting a-amylase activity. These might help prolong blood glucose response and hence control the postprandial glucose concentration. PLP could also decrease pancreatic lipase and protease activities, which may help lower the levels of serum lipids and modify protein digestibility. In addition, PLP was able to bind bile acids and may reduce cholesterol level. These results suggested that PLP may have potential benefits for human intestinal function and might be used as a potential ingredient in functional food applications. (C) 2012 Elsevier B.V. All rights reserved.