Hydroxyapatite-fucoidan nanocomposites for bone tissue engineering

Hydroxyapatite (HAp) is the promising biomaterials to construct the article bone from the last two decades. In the present study, we have developed hydroxyapatite-fucoidan (HApF) nanocomposite for bone tissue engineering and subsequently characterized by different analytical techniques for bone graft substitute. The chemical characterization suggested that the prepared nanocomposite HApF have amorphous nature, crystal size between 41 and 153 nm was observed. The biochemical characterization inferred that the prepared nanocomposite were non-toxic and mineralization effect of HApF was observed two times higher then HAp. Hence, HApF is the promising biomaterial and could be used for bone tissue construct. (C) 2013 Elsevier B.V. All rights reserved.