期刊
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
卷 45, 期 4, 页码 330-337出版社
ELSEVIER
DOI: 10.1016/j.ijbiomac.2009.08.002
关键词
N-heterocyclic chitosan derivatives; Aerogel; Rheological studies; Biological activity
资金
- Royal Society of Chemistry
The novel N-heterocyclic chitosan aerogel derivatives were prepared by reacting 79% deacetylated chitosan separately with 4-pyridinecarboxaldehyde and 2,6-pyridinedicarboxaldehyde followed by subsequent solvent exchange into acetone, filteration and lyophilization. The identity of the Schiff bases was confirmed by UV-vis absorption spectroscopy and Fourier transform infrared (FTIR) spectroscopy. The N-heterocyclic chitosan derivatives were evaluated by X-ray diffraction (XRD), thermo-gravimetric analysis (TGA), differential scanning calorimetry (DSC), scanning electron microscopy (SEM), theological studies and biological activity. Overall, the N-heterocyclic chitosan derivative based gels open new perspectives in biomedical applications. (C) 2009 Elsevier B.V. All rights reserved.
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