期刊
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
卷 45, 期 3, 页码 260-264出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.ijbiomac.2009.06.002
关键词
Chitin hydrogel; Chitin membranes; Biomaterials; Bioactivity; Cell studies
资金
- The Department of Science and Technology, Government of India
Chitin is a novel biopolymer and has excellent biological properties such as biodegradation in the human body and biocompatible, bioabsorable, antibacterial and wound healing activities. In this work, alpha- and beta-chitin membranes were prepared using alpha- and beta-chitin hydrogel. The bioactivity studies were carried out using these chitin membranes with the simulated body fluid solution (SBF) for 7, 14 and 21 days. After 7, 14 and 21 days the membranes were characterized using SEM, EDS and FT-IR. The SEM, EDS and FT-IR studies confirmed the formation of calcium phosphate layer on the surface of the both chitin membranes. These results indicate that the prepared chitin membranes were bioactive. Cell adhesion studies were also carried out using MG-63 osteoblast-like cells. The cells were adhered and spread over the membrane after 24 h of incubation. These results indicated that the chitin membranes could be used for tissue-engineering applications. (C) 2009 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据