期刊
INTERNATIONAL JOURNAL OF ADVANCED MANUFACTURING TECHNOLOGY
卷 68, 期 9-12, 页码 2261-2269出版社
SPRINGER LONDON LTD
DOI: 10.1007/s00170-013-4839-7
关键词
Additive manufacturing; Micro-syringe deposition; Calcium polyphosphate; Sacrificial photopolymer; Bio-ceramic
资金
- Department of Defense US Army [OR090169]
This article presents a novel rapid layered manufacturing approach based on a combined additive manufacturing (AM) process and a UV-based micro-syringe deposition (mu SD) technique to be used in the fabrication of bio-ceramic structures with controlled micro-sized channels for bone and osteochondral tissue regeneration. In the proposed rapid manufacturing method, micro-scale sacrificial photopolymer networks are integrated within the manufactured part by depositing the photopolymer on selected bio-ceramic powder layers using an injection system. This AM-mu SD method along with a post-processing protocol can potentially overcome current limitations of traditional powder-based AM approaches that are restricted in terms of complexity of internal architecture and feature size. For bone or osteochondral repair applications, the material system composed of the bio-ceramic and sacrificial photopolymer, along with the post-processing protocol, must ensure that the final implants are free from manufacturing residuals that could trigger an immune response post-implantation. In this study, calcium polyphosphate bio-ceramic was used as the substrate material based on prior art, polyvinyl alcohol solution was used as the powder binding agent, and ethoxylated (10 bisphenol A diacrylate) photopolymer solution was used as the sacrificial photopolymer element. Material characterization suggests that the proposed material system along with heat treatment protocol is suitable for the targeted applications where micro-scale channels within the implant are produced by AM-mu SD.
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