期刊
INTERNATIONAL JOURNAL FOR VITAMIN AND NUTRITION RESEARCH
卷 83, 期 2, 页码 129-136出版社
VERLAG HANS HUBER
DOI: 10.1024/0300-9831/a000153
关键词
vitamin E; markers; function; requirements; recommendations
The main function of vitamin E is to protect against scavenging of reactive oxygen species; it is the primary protective agent against lipid peroxidation. Overt vitamin E deficiency is present only in patients with severe malnutrition and certain chronic diseases. The latest Recommended Dietary Allowance for vitamin E is based on the correlation between hydrogen peroxide-induced erythrocyte lysis and plasma a-tocopherol concentrations (Institute of Medicine, United States), or the prevention of lipid peroxidation (National Nutrition Societies of Germany, Austria and Switzerland, D-A-CH). According to the current recommendations, the reference plasma concentration for vitamin E is 12-46 mu mol/L (daily intake of 15-30 mg alpha-tocopherol equivalents). Epidemiological studies suggest a beneficial effect of vitamin E on cardiovascular health at a plasma concentration of 30 mu mol/L (a daily intake of similar to 50 IU). Vitamin E is also an important micronutrient for maintaining the immune system, especially in the elderly. A workshop was organized with the main objective to propose a concept for developing markers of status, functionality, and health in the field of nutritional research, in order to define desirable vitamin E requirements in healthy individuals.
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